High-efficiency micropropagation, with relatively low labour costs, has been demonstrated in this unique book detailing liquid media systems for plant tissue culture. World authorities (e.g. von Arnold, Curtis, Takayama, Ziv) contribute seminal papers together with papers from researchers across Europe that are members of the EU COST Action 843 "Advanced micropropagation systems." First-hand practical applications are detailed for crops a" including ornamentals and trees a" using a wide range of techniques, from thin-film temporary immersion systems to more traditional aerated bioreactors with many types of explant a" shoots to somatic embryos. The accounts are realistic, balanced and provide a contemporary account of this important aspect of mass propagation.

This book is essential reading for all those in commercial micropropagation labs, as well as researchers worldwide who are keen to improve propagation techniques and lower economic costs of production. Undergraduate and postgraduate students in the applied plant sciences and horticulture will find the book an enlightened treatise.

In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents the latest information from the extensive literature and research available. Evidence is now emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Thus, endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling.

The Biology of Lungfishes presents an up-to-date collection of reviews on some of the most important aspects of the life of lungfishes. The book draws on contributions from well-known experts with a long record of scientific work within their respective fields. The general natural history of the three genera of lungfishes, the fascinating fossil story, and modern ideas of lungfish phylogeny form the main part of the text. The book also covers the morphology and physiology of various organs.

Even though the gorilla is our closest living relative, information about its anatomy, and particularly its musculature, is scarce. This book is the first photographic and descriptive musculoskeletal atlas of the gorilla. It includes high-quality photographs of musculoskeletal structures from most anatomical regions of the body, along with textual information about the attachments, innervations, and weight of the reported muscles. The atlas is an up-to-date review of the anatomical variations within gorillas as well as an extensive list of the synonyms used in the literature to designate the structures covered in the book. It also contains dissection observations of other primates and vertebrates, which are crucial for examining and understanding the homologies between the muscular structures of gorillas, humans, and other taxa.

Introduction: A Multidisciplinary Approach to Understanding the Neurodevelopment of Schizophrenia; J.M. Hollister, et al. The Developing Brain: Fetal Development and Schizophrenia: Historical Observations from Teratology; W.O. McClure. Pathology of the Brain of Schizophrenics: Implications for Neurodevelopment: Neuroimaging Studies: Structural Brain Abnormalities in Schizophrenia: Distribution, Etiology, and Implications; L.T. Eyler-Zorilla, T.D. Cannon. Animal Models: Fetal Developmental Animal Model of Schizophrenia with Dopamine, Acetylcholine, and Nitric Oxide Perspective; M. Lyon, W.O. McClure. Premorbid Signs and Clinical Characteristics of Schizophrenia: Childhood Risk Factors for Adult Schizophrenia in a General Population Cohort at Age 43 Years; P. Jones, et al. Fetal Neurodevelopmental Disterbance: Sources and Consequences: Fetal Viral Infections: Fetal Viral Infection and Adult Schizophrenia: Empirical Findings and Interpretations; R.A. Machon, et al. Antibody Exposure: Disruption of Fetal Brain Development by Maternal Antibodies as an Etiological Factor in Schizophrenia; P. Laing, et al. 5 additional articles. Index.

Contains basic and up-to-date information on an emerging fish model Allows non-specialist readers to grasp the relevance of a wide research area Provides accurate and easy to access information on each of the 30 species Includes guidance for establishing a breeding colony Documents that Anemonefishes are useful model organisms for ecological, developmental and climate research

This book presents 20 selected contributions to the 18th Evolutionary Biology Meeting, which took place in September 2014 in Marseille. They are grouped under the following major themes: * Genotype to Phenotype * Genetic Mechanisms of Diversification * Evolutionary Mechanisms * Speciation and Biodiversity The aims of these annual meetings in Marseille are to bring together leading evolutionary biologists and other scientists who employ evolutionary biology concepts, e.g. for medical research, and to promote the exchange of ideas and encourage interdisciplinary collaborations. Offering an up-to-date overview of recent advances in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students.

The International Society for Gender Medicine: History and Highlights is about a major step in the improvement of quality in medicine, namely the long overdue understanding that women are different from men in every system of the body and may require different approaches in diagnosis and treatment. This is not a textbook, nor is it a scientific publication. It is the story of the International Society for Gender Medicine (IGM) as soon through the eyes of 12 pioneers of Gender and Sex Specific Medicine (GSSM) from seven countries, five of whom were the founds of IGM in 2006. It describes the development of this new science in the respective countries and academic environments of the authors, their very personal experience while promoting, and implementing their vision of GSSM, their frustrations, successes, and achievements. The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender and sex. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, cancer, osteoporosis, diabetes, obesity, and infectious diseases. This book is essential reading for all researchers, graduate students, practitioners, and anyone interested in this diverse and thriving field. From the early beginning, to the recent NIH mandate that females be included in pre-clinical as well as clinical research and that research results be reported by sex, the quick read will broaden your understanding of the history of the field and highlight where the future is headed.

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neurological development 3) Appeals to neuroanatomists, developmental biologists and clinical practitioners. 4) Persistent relevance - brain development is not going to change.

Ageing, Cancer and the Genome. Genetics of Ageing and Multifactorial Diseases; P.E. Slagboom, D.L. Knook. Ageing and Cancer: A Struggle of Tendencies; A. Derventzi, et al. Maintaining the Stability of the Genome; A. Burkle. Nuclear-Mitochondrial Interactions Involved in Biological Ageing; H.D. Osiewacz. From Genes to Functional Gene Products During Ageing; L. Brock Andersen, et al. Cells, Systems and Organisms. Ageing of Cells in Vitro; S. Shall. Stress and Energy Metabolism in Age-Related Processes; O. Toussaint, J. Remacle. Growth Factors and Ageing: The Case of Wound Healing;D. Stathakos, et al.

This practical manual on sperm analysis presents the diagnostic and therapeutic procedures that are used in andrology laboratories to analyse and assess male infertility. Diagnostic areas include: semen analysis and the biochemical, immunological and microbiological examination of human semen and spermatozoa; computer-aided sperm motility analysis; sperm ultrastructure; and assessment of sperm transport through the female tract and sperm fertilizing ability. The clinical relevance of various diagnostic procedures is also discussed. Therapeutic topics include sperm washing techniques, semen cryopreservation, and insemination procedures. The volume also covers safety in the andrology laboratory, technician training, and quality control. The text is extensively illustrated and will be an invaluable resource to all scientists and technicians who diagnose male infertility. It will also be of interest to researchers working in human gamete biology and reproductive physiology. The detailed methods described in the book are relevant to all hospital, commercial, and university laboratories involved in infertility diagnosis and treatment.

This book, first published in English in 1932, serves as an introduction to experimental embryology. This title, while covering in-depth the field of investigation, presents the general issues surrounding this particular study rather than just providing an analysis of particular results. This title will be of interest to students of introductory biology and the history of science.

The first book on zoo/captive animal behavior and how this applies to welfare. Despite growing evidence of the need to implement more suitable, naturalistic practices into zoo animal welfare, it still seems to be somewhat overlooked - this book will address this oversight. Includes specific detail and examples focusing on taxa, a huge factor in managing animals in zoos that has not previously been addressed in this way. Covers invertebrates as well as vertebrate species. Would be a recommended or core text on Zoo Biology courses, BScs in Animal Science, and Animal Welfare MScs, as well as an invaluable practitioner reference. A lot of students interested in animal behaviour are interested in zoos. Each chapter covers species-specific content include the following information: Ecology and natural history as relevant to the zoo, behaviour and welfare measures based on ecological knowledge, feeding ecology and nutritional management, mating systems and reproductive characteristics, enrichment and behavioural diversity. The chapters are consistently formatted for ease of information, with end of chapter summaries, boxes with selected enrichment devices or welfare assessment methods for assessing welfare state, and directed reading of peer reviewed and other reputable sources that help advance care. A final Part explores welfare assessment tools, quality of life, veterinary interventions and evidence-based approaches. It looks at ways to increase the value of zoo and aquarium animals by enhancing visitor interest and visitor behaviour change. Also, research needs for keepers and how to build evidence into a daily routine, as well as management of native species programmes and the future of zoo research.

During the last decade, modern technologies have made a revolutionary change in developmental biology. The molecular and cellular processes in live embryos can now be visualized thanks to technologies using fluorescent proteins. The whole genome information of a wide range of animal species has now become available, confirming the common principles that operate in every species. These and other advances in our understanding of the developmental processes during embryogenesis and tissue regeneration have put forward new principles. Those new principles will also be important in the stem cell biology, branched from developmental biology, in order to generate a particular tissue by manipulating stem cells. This book is planned to introduce these new principles to readers who are working in developmental biology and/or stem cell biology fields, with an emphasis on genetic and cellular processes.

Written by a single author in a clear and consistent writing style, presents a logical and easy to follow discussion about each phase of neural development Presents an accessible approach to developmental neurobiology for students who do not have an extensive background in neuroscience or cell and molecular biology Clear, informative, and easy-to-follow illustrations support the concepts presented in the text Highlights neurodevelopmental and neurodegenerative disorders where relevant and therapeutic approaches to neurological diseases

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neorological development 3) Appeals to neuroanatomists, developmental biologists and clinical practioners. 4) Persistent relevantce - brain development is not going to change.

Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development.

The first volume in this new series from The Center for the Study of Child and Adolescent Development at The Pennsylvania State University focuses on the relationship between the biological stress circuits and the behavioral concomitants to stress in animals and humans. The participants at this conference, a tribute to Dean Evan G. Pattishall, Jr., discuss the developmental implications of their work in relation to the periods of infancy, childhood, and adolescence. For professionals, clinicians, and researchers in clinical, developmental, experimental, and health psychology, behavioral medicine, psychiatry, psychotherapy, and the neurosciences.

The main goal of this book is to put the Darwinian tradition in context by raising questions such as: How should it be defined? Did it interact with other research programs? Were there any research programs that developed largely independently of the Darwinian tradition? Accordingly, the contributing authors explicitly explore the nature of the relationship between the Darwinian tradition and other research programs running in parallel. In the wake of the Synthetic Theory of Evolution, which was established throughout the 1930s, 1940s, and 1950s, historians and philosophers of biology devoted considerable attention to the Darwinian tradition, i.e., linking Charles Darwin to mid-Twentieth-Century developments in evolutionary biology. Since then, more recent developments in evolutionary biology have challenged, in part or entirely, the heritage of the Darwinian tradition. Not surprisingly, this has in turn been followed by a historiographical "recalibration" on the part of historians and philosophers regarding other research programs and traditions in evolutionary biology. In order to acknowledge this shift, the papers in this book have been arranged on the basis of two main threads: Part I: A perspective that views Darwinism as either being originally pluralistic or having acquired such a pluralistic nature through modifications and borrowings over time. Part II: A perspective blurring the boundaries between non-Darwinian and Darwinian traditions, either by contending that Darwinism itself was never quite as Darwinian as previously assumed, or that non-Darwinian traditions took on board various Darwinian components, when not fertilizing Darwinism directly. Between a Darwinism reaching out to other research programs and non-Darwinian programs reaching out to Darwinism, the least that can be said is that this interweaving of intellectual threads blurs the historiographical field. This volume aims to open vital new avenues for approaching and reflecting on the development of evolutionary biology.

This book, first published in English in 1932, serves as an introduction to experimental embryology. This title, while covering in-depth the field of investigation, presents the general issues surrounding this particular study rather than just providing an analysis of particular results. This title will be of interest to students of introductory biology and the history of science.

This third of 15 short atlases reimagines the classic 5-volume Atlas of Human Central Nervous System Development. This volume presents serial sections from specimens between 15 mm and 18 mm with detailed annotations, together with 3D reconstructions. An introduction summarizes human CNS development by using high-resolution photos of methacrylate-embedded rat embryos at a similar stage of development as the human specimens in this volume. The accompanying Glossary gives definitions for all the terms used in this volume and all the others in the Atlas. Features Classic anatomical atlas Detailed labeling of structures in the developing brain offers updated terminology and the identification of unique developmental features, such as germinal matrices of specific neuronal populations and migratory streams of young neurons Appeals to neuroanatomists, developmental biologists, and clinical practitioners A valuable reference work on brain development that will be relevant for decades

1) Classic anatomical atlases 2) Detailed labelling of the earliest phases of prenatal neurological development without abbreviations 3) Appeals to neuroanatomists, developmental biologists and clinical practioners 4) Persistent relevance - brain development is not going to change, but this Atlas offers updated terminology for primordial neural structures.

Why do the best-known examples of evolutionary change involve the alteration of one kind of animal into another very similar one, like the evolution of a bigger beak in a bird? Wouldn't it be much more interesting to understand how beaks originated? Most people would agree, but until recently we didn't know much about such origins. That is now changing, with the growth of the interdisciplinary field evo-devo, which deals with the relationship between how embryos develop in the short term and how they (and the adults they grow into) evolve in the long term. One of the key questions is: can the origins of structures such as beaks, eyes, and shells be explained within a Darwinian framework? The answer seems to be yes, but only by expanding that framework. This book discusses the required expansion, and the current state of play regarding our understanding of evolutionary and developmental origins.

This volume explores the diverse ways in which the evolution of human behaviour can be investigated, and confronts the most challenging aspects of the subject.

This book focuses on human anatomy and medicine and specifically on both muscular and skeletal birth defects in humans with trisomy. Moreover, this book also deals with Down syndrome, which is one of the most studied human syndromes and, due to its high incidence and the fact that individuals with this syndrome often live until adulthood, is of special interest to the scientific and medical community. This new line of inquiry is addressed to a wide audience, including medical researchers, physicians, surgeons, medical and dental students, pathologists, and pediatricians, among others, while also being of interest to developmental and evolutionary biologists, anatomists, functional morphologists, and zoologists.