The Immunological Synapse - Part B, Volume 178 (Hardcover)

The Immunological Synapse - Part B, Volume 178 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. This first volume covers various aspects on T cell and natural killer (NK) cell synapses, including imaging polarized granule release using TIRF microscopy, analysis of actin reorganization and centrosome polarization, redirected degranulation, live cell-imaging to quantify cytotoxic and chemotactic dynamics, quantification of interactions between APCs and T cells, assessment of membrane lipid state at the immunological synapse, proteomic analysis and imaging of NK-tumor cell interaction, evaluating natural killer cell effector functions against breast cancer cells derived from human tumor tissue, evaluation of chimeric antigen receptor (CAR)-modified cell immunological synapse quality using the glass-supported planar lipid bilayer, and monitoring potency of therapeutic CAR T cells. It also includes one chapter on quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, and one chapter on the murine antibody-dependent cellular phagocytosis assay.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Methods in Cell Biology
Release date:	July 2023
First published:	2023
Volume editors:	Clément Thomas • Lorenzo Galluzzi
Dimensions:	229 x 152mm (L x W)
Format:	Hardcover
Pages:	318
ISBN-13:	978-0-443-19163-3
Categories:	Books > Science & Mathematics > Biology, life sciences > Developmental biology Books > Science & Mathematics > Biology, life sciences > Molecular biology Promotions
LSN:	0-443-19163-8
Barcode:	9780443191633

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