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Evolution of Extracellular Matrix (Paperback, 2013 ed.)
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Evolution of Extracellular Matrix (Paperback, 2013 ed.)
Series: Biology of Extracellular Matrix
Expected to ship within 10 - 15 working days
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The evolution of single cells into multicellular organisms was
mediated, in large part, by the extracellular matrix. The proteins
and glycoconjugates that make up the extracellular matrix provide
structural support to cellular complexes, facilitate cell adhesion
and migration, and impart mechanical properties that are important
for tissue function. Each class of ECM macromolecule has evolved to
incorporate distinctive properties that are defined by conserved
modules that are mixed together to achieve appropriate function.
This volume provides a comprehensive analysis of how the major ECM
components evolved over time in order to fill their specific roles
found in modern organisms. The major focus is on the structural
matrix proteins, matricellular proteins, and more complex ECM
structures such as basement membranes. Adhesive proteins and their
receptors are also discussed.
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