The Biostatistics of Aging - From Gompertzian Mortality to an Index of Aging-Relatedness (Hardcover)

A practical and clarifying approach to aging and aging-related diseases Providing a thorough and extensive theoretical framework, The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness addresses the surprisingly subtlenotion with consequential biomedical and public health relevance of what it means for acondition to be related to aging. In this pursuit, the book presents a new quantitative methodto examine the relative contributions of genetic and environmental factors to mortality anddisease incidence in a population. With input from evolutionary biology, population genetics, demography, and epidemiology, this medically motivated book describes an index of aging-relatedness and also features: * Original results on the asymptotic behavior of the minimum of time-to-event random variables, which extends those of the classical statistical theory of extreme values * A comprehensive and satisfactory explanation based on biological principles of the Gompertz pattern of mortality in human populations * The development of an evolution-based model of causation relevant to mortality and aging-related diseases of complex etiology * An explanation of how and why the description of human mortality by the Gompertz distribution can be improved upon from first principles * The amply illustrated analysis of real-world data, including a program for conducting the analysis written in the freely available R statistical software * Technical appendices including mathematical material as well as an extensive and multidisciplinary bibliography on aging and aging-related diseases The Biostatistics of Aging: From Gompertzian Mortality to an Index of Aging-Relatedness is an excellent resource for practitioners and researchers with an interest in aging and aging-related diseases from the fields of medicine, biology, gerontology, biostatistics, epidemiology, demography, and public health.

General

Imprint:	John Wiley & Sons
Country of origin:	United States
Release date:	May 2014
First published:	2014
Authors:	G Levy
Dimensions:	242 x 157 x 22mm (L x W x T)
Format:	Hardcover
Pages:	272
ISBN-13:	978-1-118-64585-7
Categories:	Books > Medicine > Clinical & internal medicine > Geriatric medicine Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics Promotions
LSN:	1-118-64585-5
Barcode:	9781118645857

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