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Reviews of Physiology, Biochemistry and Pharmacology - Special Issue on Cyclic GMP (Paperback, Softcover reprint of the original 1st ed. 1999)
Loot Price: R1,534
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Reviews of Physiology, Biochemistry and Pharmacology - Special Issue on Cyclic GMP (Paperback, Softcover reprint of the original 1st ed. 1999)
Series: Reviews of Physiology, Biochemistry and Pharmacology, 135
Expected to ship within 10 - 15 working days
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This special volume provides up-to-date information on research
dealing with the regulation of the biosynthesis and degradation of
cyclic GMP and with the regulation of physiological systems by
cyclic GMP. The publication of this volume could not have come at a
more appropriate time, with significant work in this area having
led to our current understanding of the role of nitric oxide in
signal transduction, and the 1998 Nobel Prize in Medicine and
Physiology for Furchgott, Murad and Ignarro. Moreover, the
introduction in early 1998 of sildenafil (Viagra), a selective
inhibitor of a cyclic GMP phosphodiesterase, for the treatment of
erectile dysfunction in men represents the first successful
therapeutic application of an agent designed to alter the activity
of a molecular target in a cyclic GMP pathway.
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