Malaria is one of the most prevalent infectious diseases worldwide.
Severe malaria leads to the death of close to two million
individuals every year. Plasmodium falciparum, the causative agent
of the most severe form of malaria is becoming increasingly
resistant to current drugs, including artemisinin. This book
presents current advances and comprehensive material in the biology
of the parasite responsible for the most enduring and devastating
disease of mankind. This book addresses P. falciparum infection and
severe malaria, the role of heat shock proteins in the development
and pathogenicity of the parasite, the biosynthesis of isoprenoid,
specifically the methylerythritol phosphate (MEP) pathway in the
erythrocytic stages of the parasite is described.
General
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