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Adverse Events with Biomedicines - Prevention Through Understanding (Paperback, Softcover reprint of the original 1st ed. 2014)
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Adverse Events with Biomedicines - Prevention Through Understanding (Paperback, Softcover reprint of the original 1st ed. 2014)
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This monograph gathers and evaluates data on adverse events (AEs)
associated specifically with those "biomedicines" - monoclonal
antibodies, fusion proteins, and cytokines - that have recently
entered therapeutic use in humans. All AEs observed when using each
member of this new drug class are covered, with a view to improving
understanding of pathogenesis, facilitating prevention, monitoring,
and control, and contributing to the development of better drugs
that provide benefits while minimizing risk. Further aspects here
examined include the role of drug mechanisms of action and
immunogenicity in relation to AEs outcome and induction of systemic
syndromes. Additional data on AEs in off-label treatments are also
considered. Electronic data sheets, downloadable from Springer
Extra Materials platform, include more detailed safety data as well
as additional basic information on product characteristics, pre-
and post-marketing AEs classified according to frequency, and
system/organ targeting. Data on excipients and selected information
on drug interactions and associations are also provided. Adverse
Events with Biomedicines: Prevention Through Understanding will
serve as a detailed, practical guideline to this important new
area, which demands the attention of clinicians, immunologists,
oncologists, allergologists, public health professionals, and drug
companies.
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