Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to characterize natural products, including -omic technologies, phyto-chemical analysis, hyphenated techniques, and many more.

'Trease and Evans' is an encyclopedic reference work on pharmacognosy - the study of those natural substances, principally plants, that find a use in medicine. Its popularity and longevity stem from the book's balance between classical (crude and powdered drugs' characterization and examination) and modern (phytochemistry and pharmacology) aspects of this branch of science, as well as the editor's recognition in recent years of the growing importance of complementary medicines, including herbal, homeopathic and aromatherapy. No other book provides such a wealth of detail. A reservoir of knowledge in a field where there is a resurgence of interest - plants as a source of drugs are of growing interest both in complementary medicine fields and in the pharmaceutical industry in their search for new 'lead compounds'. Dr Evans has been associated with the book for over 20 years and is a recognised authority in all parts of the world where pharmacognosy is studied, his knowledge and grasp of the subject matter is unique. Meticulously referenced and kept up to date by the editor, new contributors brought in to cover new areas. New chapter on 'Neuroceuticals'. Addition of many new compounds recently added to British Pharmacopoeia as a result of European harmonisation. Considers development in legal control and standardisation of plant materials previously regarded as 'herbal medicines'. More on the study of safety and efficacy of Chinese and Asian drugs. Quality control issues updated in line with latest guidelines (BP 2007).

High pressure liquid chromatography-frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening).

Designed to help students incrementally build their knowledge of fundamental concepts of medicinal chemistry and their applications to therapeutic decisions, it is progressively organized. Specific sections of the text have been updated to make potentially confusing concepts easier to understand. Numerous examples and review questions further reinforce learning and analytical skills. This updated and expanded edition of the popular textbook, Basic Concepts in Medicinal Chemistry,, has been enhanced with new subject material, numerous self-assessment tools, and special features to advance and strengthen the learning process. New in the Third Edition Enhanced explanations, discussions, and examples in many key chapters. Additional summary tables to help readers better select the proper drug binding interaction. Expanded discussion on Pharmacogenomics, including multiple specific examples. Updated examples throughout the text to include a wider range of drugs and drug classes Increased focus on application of concepts to therapeutic decisions and pharmacy practice.

Drugs in Use: Case Studies for Pharmacists and Prescribers helps you to bridge the gap between theoretical knowledge about medicines and the practical application to your patients. With an ever increasing shift of focus from theory to practice this book promotes evidence-based medicine and illustrates how you can optimise drug therapy in response to the needs of your individual patients. It will prove a valuable resource to pharmacists and prescribers. The cases have been updated to reflect recent changes in medicines use and this new edition boasts: New evidence concerning optimal care; Additional coverage of situations with difficulties in treatment optimisation; Significant focus on major advances in therapeutics; Self study questions and answers within each case. With self study questions and answers to accompany each case, you will find this a useful resource throughout your career. As a student, it will assist your studies and as a practicing pharmacist or prescriber in hospital or community it will aid your continuing professional development.

Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants' historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.

Get everything you need to prepare for a successful career as a pharmacy technician in one easy-to-read textbook! Useful from day one through graduation, Mosby's Pharmacy Technician: Principles and Practice, 6th Edition includes comprehensive information on pharmacy practice, anatomy and physiology, math calculation, and pharmacology. Built from the ground up to map directly to American Society for Health-System Pharmacists (ASHP) accreditation competencies and to the accepted certification exams, this approachable text covers everything from processing and handling of medications and medication orders to patient safety, quality assurance, and regulation and compliance. It also features a rich art program with equipment close-ups, clinical procedures and processes, and body system illustrations that bring the content to life and visually reinforce your understanding of key concepts. With its clear writing, expert insight, and engaging study tools, this text will help you develop a solid foundation in the pharmacy content you need to pass the board examination and launch a successful and rewarding career. Comprehensive coverage of pharmacy practice, A&P, and pharmacology supports classroom success and board exam preparation. Step-by-step, illustrated procedures provide rationales for key skills and competencies. Study practice includes review questions at the end of each chapter, an exam-review appendix with sample questions, and online review questions. Scenario boxes help you develop real-world problem-solving skills. Mini drug monographs provide drug information summaries and photos for commonly prescribed medications. Tech Notes and Tech Alerts offer practical tips for on-the-job accuracy and efficiency. NEW! Additional content ensures thorough coverage of all entry-level and many advanced ASHP accreditation competencies, including: Wellness, disease prevention, and immunizations Medication compliance and point-of-care testing Professional and regulatory standards Medication requiring special handling and documentation Nonsterile and sterile compounding Advanced Pharmacy Technician duties

Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines.

Regulatory Affairs in the Pharmaceutical Industry is a comprehensive reference that compiles all the information available pertaining to regulatory procedures currently followed by the pharmaceutical industry. Designed to impart advanced knowledge and skills required to learn the various concepts of regulatory affairs, the content covers new drugs, generic drugs and their development, regulatory filings in different countries, different phases of clinical trials, and the submission of regulatory documents like IND (Investigational New Drug), NDA (New Drug Application) and ANDA (Abbreviated New Drug Application). Chapters cover documentation in the pharmaceutical industry, generic drug development, code of Federal Regulation (CFR), the ANDA regulatory approval process, the process and documentation for US registration of foreign drugs, the regulation of combination products and medical devices, the CTD and ECTD formats, and much more.