An extraordinary compendium of information on herbal medicine, Medicinal Plants of the World, Volume 3 comprehensively documents the medicinal value of 16 major plant species widely used around the world in medical formulations. The book's exhaustive summary of available scientific data for the plants provides detailed information on how each plant is used in different countries, describing both traditional therapeutic applications and what is known from its use in clinical trials. A comprehensive bibliography of over 3000 references cites the literature available from a wide range of disciplines. This book offers an unprecedented collection of vital scientific information for pharmacologists, herbal medicine practitioners, drug developers, medicinal chemists, phytochemists, toxicologists, and researchers who want to explore the use of plant materials for medicinal and related purposes.

In Buprenorphine Therapy of Opiate Addiction, participating physicians and toxicologists summarize and evaluate their experiences with five years of intensive buprenorphine therapy. They cover all aspects of its use, including the pharmacology, conditions of delivery, risks from use with other psychoactive drugs, toxicology and related deaths, as well as its testing in blood, urine, tissue, and hair. Special attention is given to comparing the long-term care of opiate-dependent patients using high-dose buprenorphine vs methadone, and to explaining the differences in treatment, administration, and delivery. The authors also describe how buprenorphine is currently prescribed and monitored in France and Australia, and review all the latest advances in analytical techniques for the determination of buprenorphine and its metabolites in biological fluids and tissues.

The growth in chemotherapy has led to a great need for all those involved to be familiar with safe procedures based on best evidence-based practice. Practical Chemotherapy: a multidisciplinary guide is a comprehensive and straightforward guide describing over 70 widely used chemotherapy regimens, helping to make their prescription and administration safer and less problematic. Checklists throughout the book are specifically tailored for the needs of each professional group involved in treatment, and are intended to help prevent potentially serious mistakes that can occur. This book is unique in its practical emphasis and will be invaluable for doctors, pharmacists and nurses working in oncology and haematology.

Drug misuse is a major challenge for health professionals in the twenty-first century, and community pharmacy holds a key place in the management of prescribed medication, the provision of health education and promotion messages to drug users. Two decades ago there would have been no need for a book which described the role of community pharmacy in services for drug users, however, with the increasing numbers of individuals injecting drugs and the advent of HIV, community pharmacists have found themselves caught in the ever-expanding demand for their services. The quality practice of tomorrow will hinge on there being trained and competent practitioners working in a variety of community pharmacy settings.
This book aims to provide the reader with a grounding in the historical, research and practical aspects of community pharmacy and drug misuse. It is written by experienced professionals using a practical and evidence-based approach, aimed at all students of pharmacy, pre-registrayion pharmacists, community pharmacists working with drug users and anyone involved in developing and managing primary healthcare for drug misusers.

Cardiovascular disease is the leading cause of death in the United States and is the focus of ongoing research. Consequently, treatment of cardiovascular disorders is among the most highly evidence-based area of medicine and pharmacy practice.

Quick Reference to Cardiovascular Pharmacotherapy provides important guidelines and standards of care in the pharmacological management of cardiovascular diseases. It begins with the management of cardiovascular risk factors and continues with important pharmacotherapeutics. In addition, the authors tackle crucial pharmacotherapeutic problems related to managing patients with cardiovascular diseases, such as drug-induced cardiovascular side effects and alternative pharmacotherapy for managing cardiovascular diseases. With numerous tables and charts utilized throughout, the pocketbook also contains important dosing information applicable specifically to cardiac patients.

Furthermore, based on their experience, the contributors offer important clinical pearls to help deal with commonly encountered clinical problems in daily practice. Quick Reference to Cardiovascular Pharmacotherapy provides health care professionals and students a concise, quick, and authoritative summary of how to utilize pharmacological agents for the management of cardiovascular disease.

Identify effective means of detection of particles Understand and interpret current environmental, GMP and other standards, and requirements for contamination control Learn the sources and characteristics of contaminant particles Set up requirements and test methods for injectable solutions and medical devices Conduct visual inspections, light extinction particle counting, airborne particle counting, and environmental monitoring Validate particle counting instrument systems Sample and collect particulate matter for analysis This book offers practical applications addressing the specifics of contamination, including particle origination, characterization, identification, and elimination, with a special focus on quality considerations. Written by an industry expert, this material offers a clear and concise understanding of particle populations and their control in stability, efficacy, and predictability in the manufacture of healthcare products. Complete with a full-color insert of micrographs illustrating commonly encountered particulate matter and over eighty figures, tables, and charts.

This book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. DMPK in Drug Discovery - Guide to Data Interpretation and integration leverages the prior knowledge from the first book that covers the basics of each concept (Drug Metabolism and Pharmacokinetics Quick Guide). This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures, and case studies that can facilitate drug discovery. The case studies are intended to be short and relevant to the topic discussed and present another dimension to the discussions.

Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.

This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.

Pharmaceutical giants have doubled their investments in drug development in the past decade only to see new drug approvals remain constant. This book investigates and highlights a set of proactive strategies aimed at generating sustainable competitive advantage based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of cooperation and internationalization, such as open innovation in the early phases of R&D. Our findings are illustrated by cases from Europe, the US, and Asia.