This is the first detailed treatment of the long-standing,
previously unresolved controversy surrounding the nature of
senescence in clonal cultures. Part historical review of the
literature, part detective story, Sex and Death in Protozoa
presents a comprehensive but entertaining discussion of the
sometimes contradictory evidence for protozoan senescence and the
rejuvenating effects of sex in these organisms. Drawing on Hermann
Muller's "ratchet model," Dr. Bell demonstrates in a quantitative
fashion how genetic recombination (an intrinsic part of the sexual
process) can eliminate the deleterious effects of accumulated
mutations in clonal cultures and provide the rejuvenating effects
associated with mating. This well written account by one of the
leading authorities in the field is indispensable reading for those
interested in the genetics and cell biology of protozoa, and more
generally, those researchers and students interested in the
phenomenon of senescence.
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