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Imaging of Hypoxia - Tracer Developments (Hardcover, 1999 ed.)
Loot Price: R4,301
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Imaging of Hypoxia - Tracer Developments (Hardcover, 1999 ed.)
Series: Developments in Nuclear Medicine, 33
Expected to ship within 12 - 17 working days
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Hypoxia, i.e. insufficient availability of oxygen within the
tissue, is a more serious problem than realized in clinical routine
work, although a large variety of theoretical and experimental data
give clearly proven indications. During incidences and progress of
many types of diseases hypoxia may enhance development and progress
of the disease and, furthermore, decrease chances of efficient
treatment of, e.g., tumors. Hypoxic tumor cells are up to three
times more resistant towards radiation therapy than normoxic cells.
With a diagnostic tool such as provided by hypoxia tracers suitable
for PET and SPECT imaging, the particular tissue situation becomes
detectable and, thus, treatable. Although the clinical importance
of hypoxia imaging is obviously great, to date neither the clinical
nor the scientific community at an international level has focused
many research activities on the hypoxia problem. As the result of a
workshop held by the Section for Radiopharmacy in TA1/4bingen, this
book collects observations and findings in order to stimulate the
on-going research resulting in important clinical applications.
Hypoxia imaging is needed in areas of cardiology, neurology and
oncology. Additional applications are to be expected in the field
of diabetes, infections and organ transplantation. Therefore, the
book addresses those who are basically involved in research in
radiochemistry and radiopharmacy as well as those dealing with all
biological aspects and facing direct clinical applications.
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