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Myocarditis Cardiomyopathy - Selected Problems of Pathogenesis and Clinic (Paperback, Softcover reprint of the original 1st ed. 1983)
Loot Price: R2,825
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Myocarditis Cardiomyopathy - Selected Problems of Pathogenesis and Clinic (Paperback, Softcover reprint of the original 1st ed. 1983)
Series: International Boehringer Mannheim Symposia
Expected to ship within 10 - 15 working days
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Primary myocardial disease, nowadays referred to as congestive or,
more re cently, dilating cardiomyopathy, comprises disorders of
varied etiology. Most oftenly the pathogenetic mechanism or
causative agent remains unknown. The significance of inflammatory
processes, i.e. myocarditis in a wider sense as the etiologic
factor has been debated for many years. In a few instances,
especially in children and newborns viral infections can be
incriminated. In adults this etiology can be ascertained only in
rare instances. And it has remained entirely uncertain if, or under
which circumstances, and how often virus myocarditis can lead to a
chronic disorder of the heart, namely dilated cardiomyopathy.
Although it would seem conceivable that an immunological response
to an infectious agent might induce parenchymal damage with
subsequent loss of cellular function and structural integrity of
permanent nature, i.e. dilatation, functional deterioration and
dysrhythmias, numerous attempts to establish such a pathogenetic
mechanism have not yet furnished convinicing results. Therefore the
reader will direct his attention specifically to the respective
contribution in this volume. Morphologic studies have yielded a
host of new and intriguing findings in cardiomyopathy, but have
likewise failed to settle the basic question as to which etiology
can be held responsible in a given case, especially if an inflam
matory process can be incriminated. Specific processes such as
sarcoidosis of the heart undoubtedly furnish examples of chronic
inflammation as a cause of dilating cardiomyopathy. This disorder,
however, as a specific inflammato ry myocardial affection, i.e.
myocarditis, is encountered only infrequently."
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