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Enantioselective Cobalt-catalysed Transformations (Hardcover)
Loot Price: R4,237
Discovery Miles 42 370
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Enantioselective Cobalt-catalysed Transformations (Hardcover)
Series: Catalysis Series, Volume 35
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With a foreword from leading organic chemist Professor Paul Wender,
this book collects the major developments reported in the past
thirty years in the field of enantioselective reactions promoted by
chiral cobalt catalysts, illustrating the power of these green
catalysts to provide all types of organic reactions from the basic
to completely novel methodologies. The search for new methodologies
to prepare optically pure products is one of the most active areas
of research in organic synthesis. Of the methods available for
preparing chiral compounds, catalytic asymmetric synthesis has
attracted the most attention. In particular, asymmetric
transition-metal catalysis is a powerful tool for performing
reactions in a highly enantioselective fashion. Efforts to develop
new asymmetric transformations have previously focused on the use
of rare metals such as titanium, palladium, iridium and gold.
However, the ever-growing need for environmentally friendly
catalytic processes has prompted chemists to focus on the more
abundant and less toxic first-row transition metals, such as
cobalt, to develop new catalytic systems. The ability of cobalt
catalysts to adopt unexpected reaction pathways has led to an
impressive number of enantioselective cobalt-promoted
transformations being developed over the past three decades. These
have included the synthesis of many different types of products,
often under relatively mild conditions and with remarkable
enantioselectivities. This book is a useful reference resource for
chemists, both academic and industrial, working in organic
synthesis and interested in greener or more economical catalytic
alternatives.
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