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ICRP Publication 131 - Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection (Paperback)
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ICRP Publication 131 - Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection (Paperback)
Series: Annals of the ICRP
Expected to ship within 12 - 17 working days
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This report provides a review of stem cells/progenitor cells and
their responses to ionising radiation in relation to issues
relevant to stochastic effects of radiation which form a major part
of the ICRP system of radiological protection. Current information
on stem cell characteristics, maintenance and renewal, evolution
with age, location in stem cell "niches", radiosensitivity to acute
and protracted exposures, is presented in a series of substantial
reviews as Annexes concerning haematopoietic tissue, mammary gland,
thyroid, digestive tract, lung, skin and bone. This foundation of
knowledge of stem cells is used in the main text of the report to
provide a biological insight to issues such as the
linear-no-threshold (LNT) model, cancer risk among tissues,
dose-rate effects and changes in the risk of radiation
carcinogenesis by age at exposure and attained age.
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