Molecular and Cellular Biology of Multidrug Resistance in Tumour Cells (Hardcover)

1 Characteristics of Multidrug Resistance in Human Tumor Cells.- 2 Development of Multidrug Resistance in Rodent Cell Lines.- 3 Cloning and Characterization of Mouse mdr Genes.- 4 Isolation and Characterization of the Human MDR (P-Glycoprotein) Genes.- 5 Amplification of Several Different Genes in Multidrug-Resistant Chinese Hamster Cell Lines.- 6 Molecular and Cytogenetic Analysis of Multidrug Resistance-Associated Gene Amplification in Chinese Hamster, Mouse Sarcoma, and Human Neuroblastoma Cells.- 7 Karyotype and Amplicon Evolution during Stepwise Development of Multidrug Resistance in Djungarian Hamster Cell Lines.- 8 Chromosome Localization of P-Glycoprotein Genes in Drug-Sensitive and -Resistant Human Cells.- 9 Structure and Evolution of P-Glycoproteins.- 10 Drug Accumulation and Binding in P-Glycoprotein-Associated Multidrug Resistance.- 11 Binding of Drugs and ATP by P-Glycoprotein and Transport of Drugs by Vesicles from Human Multidrug-Resistant Cells.- 12 Protein Changes in Multidrug-Resistant Cells.- 13 Membrane Lipids of Multidrug-Resistant Cells: Chemical Composition and Physical State.- 14 Expression of the MDR1 Gene in Normal Human Tissues.- 15 Expression of the Multidrug Resistant Gene in Human Cancer.- 16 Immunohistochemical Analysis of P-Glycoprotein Expression in Normal and Tumor Tissues in Humans.- 17 Quantitative Estimation of MDR1 mRNA Levels by Polymerase Chain Reaction.- 18 Collateral Sensitivity of Multidrug-Resistant Cells.- 19 Reversal of Multidrug Resistance by Calcium Channel Blockers and Other Agents.- 20 Growth Inhibition of Multidrug-Resistant Cells by Monoclonal Antibodies against P-Glycoprotein.- 21 P-Glycoprotein-Mediated Drug Resistance: Puzzles and Perspectives.

General

Imprint:	Kluwer Academic / Plenum Publishers
Country of origin:	Netherlands
Release date:	1991
First published:	April 1991
Editors:	Igor B. Roninson
Dimensions:	230mm (L)
Format:	Hardcover
Pages:	400
ISBN-13:	978-0-306-43547-8
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	0-306-43547-0
Barcode:	9780306435478

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