Jason Woolford's thesis describes for the first time, a double 3]2]
photocycloaddition of alkenes onto aromatic rings. Modern synthetic
chemistry relies on the ability of researchers to uncover new and
more efficient ways of creating highly complex structures. This
work describes a novel, environmentally friendly photochemical step
that converts in one pot, trivial starting materials into otherwise
difficult to construct fenstrane frameworks. The rigid cores of
these frameworks have significant potential in drug design.
Moreover, the novelty of this work overtakes many other methods for
the creation of chiral centres. No less than seven chiral centres
are created in the photochemical step together with the formation
of four carbon-carbon bonds and multifused rings. Jason's
innovative work has been the subject of several publications in
peer-reviewed journals."
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