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Translational Pain Research - Volume 1 - Current Status & New Trends (Hardcover)
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Translational Pain Research - Volume 1 - Current Status & New Trends (Hardcover)
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Basic science and clinical pain research is particularly
challenging for several reasons. First, pain is a subjective
experience in response to nociception that follows actual or
potential tissue damage. Since the ability to respond to this
warning signal is essential for our survival, the nociceptive
system that produces and transmits nociceptive signals is
remarkably redundant and involves diffuse regions of the central
nervous system. Second, unlike other sensory modalities, pain is a
multi-dimensional experience including at least cognitive,
affective, and sensory-discriminative components. Third, pain
experiences can be influenced by psychological, socioeconomic,
cultural, and genetic predispositions, making it exceedingly
complicated to study pain and pain modulation. In this first
volume, the current status and new trends of pain research are
selectively discussed in order to take a critical and constructive
look at the achievements of basic science research that have made
significant differences in clinical pain management as well as the
gaps between basic science research and clinical pain management.
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