The application of molecular technology in clinical diagnosis is a
rapidly developing area and is predicted to greatly improve the
speed, efficiency, and accuracy of diagnostic medicine. The editors
of this book have commissioned an excellent series of chapters
representing two key molecular diagnostic areas: cancer and
infectious diseases. The cancer section deals with the challenges
in identifying genetic, epigenetic, and transcriptomic biomarkers.
The infectious disease section describes the current clinical
applications of molecular diagnostics for the detection of viral,
bacterial, and fungal pathogens, as well as an example of the use
of molecular diagnostics outside the clinic environment. A
cautionary tale describing what can go wrong when molecular methods
are applied incorrectly is also provided and makes fascinating
reading. A substantial component of the book is dedicated to the
process of translating a preclinical test to the bedside and
describes the progress in the near patient point-of-care molecular
diagnostics market. This is a fundamental consideration for
successful translation of diagnostics tests from bench to bedside
and is crucial for molecular diagnostics to have an impact on
patient care. The final chapter offers a prediction of future
trends in the molecular diagnostics of infectious diseases. This
volume is essential reading for anyone involved in the development
or application of molecular diagnostics and is recommended for all
clinical diagnostics laboratories.
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