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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Combination Therapy in Hypertension (Paperback, 2011 ed.)
Loot Price: R1,331
Discovery Miles 13 310
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Combination Therapy in Hypertension (Paperback, 2011 ed.)
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For over 30 years, the stepped care approach has been used in the
management and treatment of hypertension. This approach advocates
the use of initial monotherapy to reach the desired blood pressure,
and the subsequent use of additional drugs with complementary modes
of action, until the target BP is achieved. However, current
control rates for hypertension suggest that such an approach may be
outdated and no longer effective in the management of hypertension.
Clinical trials have shown that more than 50% of patients require a
combination of drug therapies to achieve their target BP. Some
proponents of combination therapy have argued that the risk of
adverse side effects and non-compliance will be lower than that
compared to monotherapy, which initially requires higher doses to
be administered to be effective. Consequently, there have been
increasing calls of the necessity for a much more combined approach
in the treatment of hypertension. Adding to this, Combination
Therapy in Hypertension will cover current control rates of blood
pressure worldwide, the benefits of monotherapy and combination
therapy, examine the effectiveness, risk of adverse effects,
compliance, and cost of the available therapies and will also
include information on relevant outcome studies.
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