Vasopressin is a hormone which has an increasingly important
profile. Not only does it play a physiologically significant role
in renal water regulation but it also has other renal actions and
plays a role in overall cardiovascular control. Even more
interesting is the recent growing interest in its potential effects
on the brain, notably its influence on specific behaviours. This
monograph about the polypeptide vasopressin covers all aspects
relating to the production, control of release, and actions of this
molecule within the body, including its roles as a hormone and as a
central neurotransmitter. A consideration of the evolution of the
molecule across the species and a brief historical perspective are
also included. Clinical conditions associated with hypo- and
hyper-production states are considered together with aspects of
treatment, in addition to other clinical correlates.
General
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