The use of stem cells to help with lung regeneration and repair is
a novel therapy which could help phase out the need for
conventional surgical or pharmacological approaches currently
employed to treat diseases of the lung or other organs. The present
book explores all avenues of this new form of medical care, moving
swiftly, but in depth, from the basic science of lung development,
to the analyses of different stem cell types available for
regeneration and on to the application of this knowledge base in
initial clinical trials. In this volume a stellar group of
researchers converge, from different angles, to help towards
clarifying the basic mechanisms of lung repair. These range from
basic concepts of regeneration and lung development, the analyses
of a variety of cell types that may be involved in lung repair, to
ways of creating complex lung structures, including artificial and
bioartificial lungs. The book offers an insight into repair
mechanisms of the diseased lung, the role of specific lung niches
and provides information on initial clinical trials as well as the
use of stem cells as vehicles for gene therapy. Ingenious
technological aspects of assessing stem cell engraftment of stem
cell bioprocessing are also included in this volume.
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