The authors summarise advances in human pluripotent stem
cells-derived erythroid development and molecular regulatory
mechanisms. This research may provide a new perspective on human
embryo erythropoiesis and a possible treatment for some
hematological diseases. Erythrocytes are well equipped to carry out
their functions due to a dynamic cell membrane, their inherent
shape and lack of organelles and cytoplasmic viscosity. As such,
the following section focusses on the causes of these modifications
and their clinical implications. As an example of complexity in
research towards the development of erythrocyte membrane-based drug
delivery systems starting from animal erythrocyte, morphological,
biochemical and drug release profiles will be reviewed in the
penultimate chapter. The final chapter investigates the
electrochemical behavior of erythrocytes at platinum, carbonaceous,
and optically transparent electrodes via polarization and
coulometric measurements. The order of magnitude of the quantity of
electrons transferred between erythrocytes and electrodes was
determined, and potential ranges showing indifference of the
electrode toward red blood cells were identified.
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