Oncogenic transcription factors are an increasingly important
target for anticancer therapies. Inhibiting these transcription
factors could allow tumour cells to be "reprogrammed", leading to
apoptosis or differentiation from the malignant phenotype. As the
use of kinase inhibitors is gradually declining, transcription
factor inhibition is the next hot topic for oncology research and
merits much attention. This book highlights recent progress in the
development of small-molecule inhibitors of oncogenic transcription
factors. It also presents the evidence that this important protein
class can be modulated in a number of ways to develop novel classes
of therapeutic agents. The broad range of aspects covered by the
book is noteworthy and renders it enormously valuable. This title
serves as a unique reference book for postgraduates, academic
researchers and practitioners working in the fields of
biochemistry, biotechnology, cell and molecular biology and
bio-inorganic chemistry.
General
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