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Influence of Tumor Development on the Host (Hardcover, 1989 ed.)
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Influence of Tumor Development on the Host (Hardcover, 1989 ed.)
Series: Cancer Growth and Progression, 3
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Recent experimental evidence has made it increasingly clear In
particular, this volume reviews the discrete steps involved that
the properties of invasive, malignant cells during tumor in
metastatic invasion: the interaction of invasive tumor cells
development substantially impact on the host. This is under with
extracellular matrices, the basement membrane, attach scored by a
variety of biochemical properties of tumor cells ment to
extracellular matrices, local proteolytic degradation during their
differentiation and metastatic dissemination. of matrices, and the
locomotion of invasive tumor cells These properties can be analyzed
at different stages of tumor through such areas of localized
degradation. The critical growth and progression and this volume
explores the role of the cell surface in secondary tumor formation
is characteristics of primary tumors as well as the shared reviewed
as are important advances in the molecular biology characteristics
of both primary and secondary tumors. of metastasis initiation and
maintenance. Recent advances The primary tumor comes into existence
following in the role of DNA methylation in the generation of tumor
preneoplastic biochemical and cellular events that ultimate cell
heterogeneity and tumor progression are also critically ly result
in malignant transformation. Various aspects of summarized.
Chapters in this volume also review molecular metabolism,
predetermined by nutritional status, often play aspects of
metastatic progression, and the use of the tech a basic role.
Obesity, for example, is cancer-promoting. Cell nologies of DNA
transfection and somatic cell fusion in the surface carbohydrates,
cytoskeletal proteins, glycoproteins, exploration of molecular
aspects of metastatic progression.
General
Imprint: |
Kluwer Academic Publishers
|
Country of origin: |
United States |
Series: |
Cancer Growth and Progression, 3 |
Release date: |
December 1988 |
First published: |
1989 |
Editors: |
L.A. Liotta
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Dimensions: |
280 x 216 x 16mm (L x W x T) |
Format: |
Hardcover
|
Pages: |
240 |
Edition: |
1989 ed. |
ISBN-13: |
978-0-89838-992-0 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Diseases & disorders >
Oncology >
General
|
LSN: |
0-89838-992-5 |
Barcode: |
9780898389920 |
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