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Proteostasis and Chaperone Surveillance (Paperback, Softcover reprint of the original 1st ed. 2015)
Loot Price: R3,649
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Proteostasis and Chaperone Surveillance (Paperback, Softcover reprint of the original 1st ed. 2015)
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Proteostasis is central to the development of various human
diseases caused due to excessive protein misfolding and the
disregulation of the protein quality control system. In this book,
respected researchers from many leading institutions contribute
their insights on proteostasis maintenance. The coverage mainly
focuses on the basics of maintaining proteostasis, the consequences
of proteostatic system failure, and how chaperone systems
constantly maintain proteostasis. In addition, the book presents in
detail different treatment strategies for diseases caused by
proteostatic system failure, as well as the inhibition of
proteostatic failure using small molecule compounds. It examines
advances in the modulation of proteopathies, providing a
comprehensive source of key mechanistic insights on these diseases.
As such, the book offers a valuable resource for beginners and more
experienced investigators alike who are looking for detailed and
reliable information on protein homeostasis, the diseases that can
develop due to related imbalances and the essential role of
molecular and chemical chaperones.
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