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Peptide And Protein Engineering For Biotechnological And Therapeutic Applications (Hardcover)
Loot Price: R3,986
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Peptide And Protein Engineering For Biotechnological And Therapeutic Applications (Hardcover)
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Peptides and proteins are crucial biomolecules in life. The
manifold functions they carry out range from molecular recognition
and signaling to catalysis and immune response. However, the native
systems are limited to a reduced toolbox of chemical
functionalities as well as tridimensional structures. Widening
these toolboxes could pave the way to engineer peptides and
proteins with enhanced properties compared to their native
counterparts and/or with structures and functions unprecedented in
Nature. Advances in the chemical and biological synthesis of
peptides and proteins, in computational tools, in molecular biology
and in high-throughput screening methods are making this realm
possible.This book aims to give an overview of the last
developments in the field of peptide and protein engineering. It
comprises a collection of chapters that span from the production of
simple non-proteinogenic building blocks and peptidic scaffolds of
different sizes and structures to more complex systems including
peptide-based nanomaterials, enzymes and artificial metalloenzymes.
Different strategies are described where chemical and biological
tools have been developed and combined to attain the desired
properties and sought functionalities.The diverse systems described
in this book highlight the progress in this important field and
represent the starting points for the development of functional
biomolecules, biomaterials and hybrid systems capable of addressing
key societal challenges of our times in relevant areas such health,
environment and energy.
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