New Approaches of Protein Function Prediction from Protein
Interaction Networks contains the critical aspects of PPI network
based protein function prediction, including semantically assessing
the reliability of PPI data, measuring the functional similarity
between proteins, dynamically selecting prediction domains,
predicting functions, and establishing corresponding prediction
frameworks. Functional annotation of proteins is vital to
biological and clinical research and other applications due to the
important roles proteins play in various biological processes.
Although the functions of some proteins have been annotated via
biological experiments, there are still many proteins whose
functions are yet to be annotated due to the limitations of
existing methods and the high cost of experiments. To overcome
experimental limitations, this book helps users understand the
computational approaches that have been rapidly developed for
protein function prediction.
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