When cells are damaged, as often occurs during trauma and metabolic
stress, a highly evolved cell healing process follows that was
designed to enhance cell survival or remove irreparably injured
cells. Following injury, cells attempt to seal breaks in their
membranes, chaperone removal or refolding of altered proteins,
repair damaged DNA, or if necessary commit to programmed cell
death.
When cell injury is too extensive to permit reparative
responses, acute cellular necrosis or apoptosis can result.
Understanding injury at the subcellular organelle and molecular
levels is essential for development of new therapeutic strategies
and for optimal management of injured victims.
In this volume, various modes of injury that can occur are
described, as well as the basic molecular healing responses and
pathways of metabolic survival or death. The approach taken here is
to look at these processes at the cellular and subcellular levels,
rather than at the tissue level, and this volume will be a valuable
resource to anyone interested in wound healing, biological stress
responses, molecular chaperones, radiobiology, biomechanics, and
biomedical engineering, as well as trauma and critical care
medicine.
"NOTE: Annals volumes are available for sale as individual books
or as a journal. For information on institutional journal
subscriptions, please visit"
"www.blackwellpublishing.com/nyas."
"ACADEMY MEMBERS Please contact the New York Academy of Sciences
directly to place your order (""www.nyas.org"). Members of the New
York Academy of Science receive full-text access to the Annals
online and discounts on print volumes. Please visit http:
//www.nyas.org/MemberCenter/Join.aspx for more information about
becoming a member.
General
Imprint: |
New York Academy of Sciences
|
Country of origin: |
United States |
Release date: |
March 2008 |
First published: |
March 2006 |
Authors: |
Lee
|
Dimensions: |
231 x 147 x 19mm (L x W x T) |
Format: |
Paperback
|
Pages: |
340 |
Edition: |
Revised |
ISBN-13: |
978-1-57331-617-0 |
Categories: |
Books >
Medicine >
Other branches of medicine >
Pathology >
Cytopathology
|
LSN: |
1-57331-617-2 |
Barcode: |
9781573316170 |
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