Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy - Targeted Therapies to Reverse Resistance (Hardcover, 2013 ed.)

This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Resistance to Targeted Anti-Cancer Therapeutics, 1
Release date:	April 2013
First published:	2013
Editors:	Benjamin Bonavida
Dimensions:	235 x 155 x 20mm (L x W x T)
Format:	Hardcover
Pages:	260
Edition:	2013 ed.
ISBN-13:	978-1-4614-7069-4
Categories:	Books > Medicine > Other branches of medicine > Pathology > Cytopathology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	1-4614-7069-2
Barcode:	9781461470694

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