Tissue engineering aims to develop biological substitutes that
restore, maintain, or improve damaged tissue and organ
functionality. To date, numerous stem cells and biomaterials have
been explored for a variety of tissue and organ regeneration. The
challenge for existing stem cell based techniques is that current
therapies lack controlled environments that are crucial for
regulating stem cell engraftment and differentiation "in vivo,"
because stem cells are rather sensitive to even minute changes in
their environment. Micro- and nanotechnology hold great potential
to fabricate biomimetic spatiotemporally controlled scaffolds as
well as control stem cell behavior and fate by micro- and nanoscale
cues.
This book presents the latest micro- and nanotechnologies used
to manipulate stem cell behaviors, which is a critical area for
regenerative medicine. Moreover, it covers and details cutting-edge
research in nano- and microfabrication techniques and biomaterials
for the regeneration of various tissues and organs, such as bone,
cartilage, craniofacial, osteochondral, muscle, bladder, cardiac,
and vascular tissues."
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