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Intermediate Filament Cytoskeleton, Volume 78 (Hardcover)
Loot Price: R3,883
Discovery Miles 38 830
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Intermediate Filament Cytoskeleton, Volume 78 (Hardcover)
Series: Methods in Cell Biology
Expected to ship within 12 - 17 working days
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Intermediate filaments are a large family of proteins that are the
cytoskeletal elements involved in a number of skin, liver,
neuromuscular, cardiac, eye and hair diseases. Intermediate
filament genes are regulated in a tissue-and cell type-specific
manner and their polymerized protein products protects the cells
and tissue they are part of against a variety of mechanical and
nonmechanical stresses. This book provides a comprehensive resource
of methodology essentials, describing a variety of essential tools
and assays for studying intermediate filaments. The book provides
user-friendly advice and protocols covering all aspects of
intermediate filaments including protein isolation and structure,
protein and gene regulation, relationship to disease and apoptosis,
and associated proteins. Both mammalian and non-mammalian systems
and animal models are covered, making this book a must-have for any
investigator wishing to study IF genes or their protein products.
* Covers intermediate filaments from crystallography, protein
chemistry, cell and molecular biology, microrheology, gene
regulation, to animal models and human disease
* Practical and user-friendly with detailed "how-to-protocols and
"tricks of the trade"
* Includes detailed tables of useful reagents, vendors and web
links
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