Developmental biologists have been driven to investigate growth
factor signaling in embryos in order to understand the regulatory
mechanisms underlying a given developmental process. Thus, it is
critical to explore the technical methods and experimental designs
for growth factor signaling in embryos.
Focusing on specific pathways or pathway components, Analysis of
Growth Factor Signaling in Embryos provides the methods and
guidelines for experimental design to study major aspects of cell
signaling in vertebrate embryos. The book covers a broad range of
topics in signaling and a variety of current model organisms.
Section I explores specific signaling pathways or pathway
components. In this section, some chapters highlight the
biochemistry of signaling pathways during development, which is
often distinctive from that observed in cell culture systems.
Section II discusses ionic regulatory mechanisms and the two
chapters in Section III examine ways of investigating gene
regulation in response to extracellular signals. Finally, Section
IV addresses emerging strategies that facilitate integrated
analyses of cell signaling" in vivo" in embryonic systems.
Featuring contributions from expert researchers, Analysis of
Growth Factor Signaling in Embryos will provide a foundation for
further explorations of the cellular regulatory mechanisms
governing vertebrate embryonic development.
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