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Molecular Basis of Specific Mechanism for Bacterial Adaptation (Paperback)
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Molecular Basis of Specific Mechanism for Bacterial Adaptation (Paperback)
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Since the appearance of Darwin's book, "The Origin of Species,"
adaptation is one of the processes that explains the diversity of
species in ecosystems. Adaptive phenomena in the 19th century and
until the mid-20th century have been analyzed in macroscopic
biological systems, however since the second half of the 20th
century and to date the development of disciplines such as
Molecular Biology, has allowed us to delve into the mechanisms that
regulate cell physiology. The molecular bases that allow explaining
the adaptation processes of microorganisms to their environment
have special relevance, because through their analysis it is
possible to size the complexity of these mechanisms that involve
receptors of a protein nature associated with transduction chains
that transport the information flow to genomic DNA, and which
subsequently involves the emission of a response through the
expression of specific genes. From the point of view of the
adaptive phenomenon analysis, the approach through the molecular
bases makes it possible to understand the enormous diversity of the
microbial world. Mainly for two reasons, on the one hand the
presence of micro gradients in the bacterial ecological niches that
are continuously fluctuating, which forces the microorganisms to a
rapid adaptation phenomenon. And on the other hand, horizontal gene
transfer phenomena, which allow bacteria the information exchange.
These two elements carry great intensity in establishing new
relationships. This phenomenon is especially relevant if it is
related to a concept that Darwin cites in the Origin of Species,
"The tangled riverbank", where it is emphasized that the new
interactions establishment is the basic driving force for the new
species generation. This mechanism is explained by the positive
feedback loop generation, whereby ecosystems with high levels of
biological diversity generate new interactions that lead to new
species, which in turn tends to make the ecosystem network more
complex. This complexity analyzed in its molecular bases allows to
generate new research questions that can be applied to other
knowledge areas, such as Biotechnology. The analysis of the
molecular bases of the microorganisms adequacy, makes it possible
to identify and characterize mechanisms that implemented in
different pharmaceutical areas and agricultural industry has led to
the product generation with high added value, a clear example of
this economic development is the enzyme industry and even
recombinant protein production. Finally, it is convenient to
emphasize the need to incorporate the analysis of the molecular
bases of adaptation from the perspective of omics techniques.
Techniques that allow the study of processes and mechanisms to be
approached from a global perspective. This book summarizes some
topics of special relevance referring to adaptive processes of
different microorganisms of special relevance both in basic and
applied research.
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