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Breast Cancer: Progress in Biology, Clinical Management and Prevention - Proceedings of the International Association for Breast Cancer Research Conference, Tel-Aviv, Isreal, March 1989 (Hardcover, 1989 ed.)
Loot Price: R4,313
Discovery Miles 43 130
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Breast Cancer: Progress in Biology, Clinical Management and Prevention - Proceedings of the International Association for Breast Cancer Research Conference, Tel-Aviv, Isreal, March 1989 (Hardcover, 1989 ed.)
Series: Developments in Oncology, 58
Expected to ship within 12 - 17 working days
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In breast cancer as in other cancers on the front line of modern
interdisciplinary research we have crossed the threshhold of new
understanding. Fueled by an awareness that breast cancer is a
leading cause of morbidity and mortality in women and honed by
rapid technological advances in molecular mechanisms, major inroads
into the darkness of this scourge have been accomplished during the
past several years. Basic laboratory and clinical research findings
must influence and in turn be influenced by efforts to detect, to
diagnose and to cure the human disease. It is indeed gratifying to
note that the efforts of scientists and clinicians from throughout
the world reported in this volume are achieving this objective. The
first section of the book focuses on the molecular and genetic
basis of breast cancer. The role of specific oncogenes in mammary
tumorigenesis using transgenic mice and mammary glands correlating
molecular events with specific stages in neoplastic development are
described and discussed. Such topics as the nature of specific
oncogenes, levels of oncogene expression, the alteration of
expression of other growth regulatory genes and the state of the
cell in which the oncogene is expressed are specifically addressed.
This section of the book is rounded out with discussions on the
potential of genetic alterations as indicators of prognosis, the
characterization of full-length cDNA codes for breast cancer
markers and the function of antigens in tuomorigenesis.
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