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Books > Medicine > Clinical & internal medicine > Paediatric medicine
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Surgery for Endocrinological Diseases and Malformations in Childhood (Paperback, 1991 ed.)
Loot Price: R1,553
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Surgery for Endocrinological Diseases and Malformations in Childhood (Paperback, 1991 ed.)
Series: Progress in Pediatric Surgery, 26
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Endocrine conditions requiring surgical intervention in the
pediatric age group are uncommon. When diagnosed, they are the
source of great in terest and, often, considerable debate. This is
understandable, since few centers and even fewer individual
surgeons can draw on vast experience of this subject. The great
divergence of opinion regarding management is also understandable
in that pediatric endocrine lesions often differ considerably from
their adult counterparts in histology, natural history and response
to treatment. Pediatric endocrine lesions are also, as a rule, less
frequently malignant. In addition to the great strides made in
surgical and anesthetic technique and operative monitoring,
progress in four areas has substantially advanced the management of
endocrine dis orders in the pediatric age group in the last decade:
imaging, pathology, pharmacology and genetics. The new imaging
tools, ultrasonography, computed tomography and magnetic resonance
imaging, have added great diagnostic possibilities. More recent
developments, such as radio nuclide imaging for the adrenal gland
and the possibility of using tagged antibodies, promise to expand
our imaging horizons even further. In the field of pathology, the
develop ment of immunocytochemical markers (e. g. , monoclonal
antibodies), the refinement in special stains and the continuous
perfection of fine needle aspiration biopsies offer great new
diagnostic as well as research capabil ities. Newer pharmacological
agents, such as the alpha and beta blockers, the calcium channel
blockers and thyroxine analogs, add a whole new level of safety to
the management of the potentially lethal pheochromocytoma.
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