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Books > Medicine > General issues > Medical equipment & techniques > Medical research
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Biomedical Aspects of Histamine - Current Perspectives (Hardcover, Edition.)
Loot Price: R5,706
Discovery Miles 57 060
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Biomedical Aspects of Histamine - Current Perspectives (Hardcover, Edition.)
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Since its identification by Sir Henry H. Dale a century ago,
histamine has become one of the most important multifunctional
biogenic amines in the field of biomedicine. The pharmacological
effects of histamine are mediated through four types of membrane
histamine receptors; H1R, H2R, H3R and H4R, which are all
heptahelical G-protein-coupled receptors. It has been known to play
the broadest spectrum of activities in various physiological and
pathological conditions including cell proliferation,
differentiation, hematopoiesis, embryonic development,
regeneration, wound healing, aminergic neurotransmission and
numerous brain functions, secretion of pituitary hormones,
regulation of gastrointestinal and circulatory functions,
cardiovascular system, as well as inflammatory reactions,
modulation of the immune response, endocrine function and
homeostasis, and other important areas. This book is a compendium
of the current state of established and investigational literature
on Histamine, its receptors and their Agonists and antagonists. It
provides a comprehensive overview of histamine biology in the field
of biochemistry, cell biology, molecular biology, immunology,
allergy, neurobiology, pharmacology, microbiology and reproductive
biology. The first section on Histamine biology and physiology
leads into subsequent sections on enzymology, pharmacology,
regulation of the immune system and cell proliferation and role in
allergic and other diseases including acid peptic diseases,
inflammatory diseases, autoimmune and cancer diseases, nervous
system, reproductive functions and hematopoiesis. The compilation
of chapters in the book presents the most recent advances in
histamine research and bridges the basic and clinical aspects of
histamine biology.
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