Biomedical Aspects of Histamine - Current Perspectives (Paperback, 2011 ed.)

Since its identification by Sir Henry H. Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacological effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic neurotransmission and numerous brain functions, secretion of pituitary hormones, regulation of gastrointestinal and circulatory functions, cardiovascular system, as well as inflammatory reactions, modulation of the immune response, endocrine function and homeostasis, and other important areas. This book is a compendium of the current state of established and investigational literature on Histamine, its receptors and their Agonists and antagonists. It provides a comprehensive overview of histamine biology in the field of biochemistry, cell biology, molecular biology, immunology, allergy, neurobiology, pharmacology, microbiology and reproductive biology. The first section on Histamine biology and physiology leads into subsequent sections on enzymology, pharmacology, regulation of the immune system and cell proliferation and role in allergic and other diseases including acid peptic diseases, inflammatory diseases, autoimmune and cancer diseases, nervous system, reproductive functions and hematopoiesis. The compilation of chapters in the book presents the most recent advances in histamine research and bridges the basic and clinical aspects of histamine biology.

General

Imprint:	Springer
Country of origin:	Netherlands
Release date:	October 2014
First published:	2011
Editors-in-chief:	Mohammed Shahid
Editors:	Nancy Khardori • Rahat Ali Khan • Trivendra Tripathi
Dimensions:	235 x 155 x 25mm (L x W x T)
Format:	Paperback
Pages:	441
Edition:	2011 ed.
ISBN-13:	978-9401784993
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical research
LSN:	940178499X
Barcode:	9789401784993

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