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Molecular Biology - Principles of Genome Function (Paperback, 3rd Revised edition)
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Molecular Biology - Principles of Genome Function (Paperback, 3rd Revised edition)
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The biological world operates on a multitude of scales - from
molecules to cells to tissues to organisms to ecosystems.
Throughout all these levels runs a common thread: the communication
and onward passage of information - from cell to cell, from
organism to organism and, ultimately, from generation to
generation. But how does this information - no more than a static
repository of data - come alive to govern the processes that
constitute life? The answer lies in the concerted action of
molecular components which cooperate through a series of
carefully-regulated processes to bring the information in our
genome to life. These components and processes lie at the heart of
one of the most fascinating subjects to engage the minds of
scientists today: molecular biology. Molecular Biology: Principles
of Genome Function offers a fresh, distinctive approach to the
teaching of molecular biology. It is an approach that reflects the
challenge of teaching a subject that is in many ways unrecognizable
from the molecular biology of the 20th century - a discipline in
which our understanding has advanced immeasurably, but about which
many questions remain to be answered. It is written with several
guiding themes in mind: - A focus on key principles provides a
robust conceptual framework on which students can build a solid
understanding of the discipline; - An emphasis on the commonalities
that exist between the three kingdoms of life, and the discussion
of differences between the three kingdoms where such differences
offer instructive insights into molecular processes and components,
gives students an accurate depiction of our current understanding
of the conserved nature of molecular biology, and the differences
that underpin biological diversity; - An integrated approach
demonstrates how certain molecular phenomena have diverse impacts
on genome function by presenting them as themes that recur
throughout the book, rather than as artificially separated topics
At heart, molecular biology is an experimental science, and a
central element to the understanding of molecular biology is an
appreciation of the approaches taken to yield the information from
which concepts and principles are deduced. Yet there is also the
challenge of introducing the experimental evidence in a way that
students can readily comprehend. Molecular Biology responds to this
challenge with Experimental Approach panels, which branch off from
the text in a clearly-signposted way. These panels describe pieces
of research that have been undertaken, and which have been
particularly valuable in elucidating different aspects of molecular
biology. Each panel is carefully cross-referenced to the discussion
of key molecular biology tools and techniques, which are presented
in a dedicated chapter at the end of the book. Beyond this,
Molecular Biology further enriches the learning experience with
full-colour, custom-drawn artwork; end-of-chapter questions and
summaries; relevant suggested further readings grouped by topic;
and an extensive glossary of key terms. Among the students being
taught today are the molecular biologists of tomorrow; these
individuals will be in a position to ask fascinating questions
about fields whose complexity and sophistication become more
apparent with each year that passes. Molecular Biology: Principles
of Genome Function is the perfect introduction to this challenging,
dynamic, but ultimately fascinating discipline.
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