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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Pathogenic Neisseria - Genomics, Molecular Biology and Disease Intervention (Hardcover)
Loot Price: R6,701
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Pathogenic Neisseria - Genomics, Molecular Biology and Disease Intervention (Hardcover)
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The human pathogens Neisseria meningitidis and Neisseria
gonorrhoeae are exquisitely adapted to life within the human
mucosa, their only natural niche. N. meningitidis is the causative
agent of rapidly transmissible meningitis and septic shock.
Vaccines developed to control this pathogen can be rendered
ineffective by the pathogen's ability to undergo antigenic
variation. In contrast, there are no current vaccination prospects
for N. gonorrhoeae, the causative agent of sexually transmitted
gonorrhoea. Historically, infections caused by N. gonorrhoeae were
treated with antibiotics. However, the recent advent of new strains
with resistance to all known antibiotics is causing such treatment
regimes to fail, necessitating the need for new and more effective
control strategies. In this book, leading Neisseria authorities
review the most important research on pathogenic Neisseria to
provide a timely overview of the field. The topics covered include:
the link between pathogenesis and important metabolic pathways *
vaccine development * antibiotic resistance * transcriptomics of
regulatory networks * regulatory small RNAs * interactions with
neutrophils * advances in humanized mouse models. An essential
guide for research scientists, advanced students, clinicians, and
other professionals working with Neisseria, the book is a
recommended text for all microbiology libraries.
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