0
Your cart

Your cart is empty

Browse All departments
Price
  • R50 - R100 (1)
  • R100 - R250 (34)
  • R250 - R500 (67)
  • R500+ (770)
  • -
Status
Format
Author / Contributor
Publisher

Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA

Blueprint - How DNA Makes Us Who We Are (Paperback): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Paperback)
Robert Plomin 1
R257 R158 Discovery Miles 1 580 Save R99 (39%) Shipped within 7 - 12 working days

'Mind-blowing ... It is a hugely important book ... His story is crucial' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

The Double Helix (Paperback): James Watson The Double Helix (Paperback)
James Watson 1
R231 R193 Discovery Miles 1 930 Save R38 (16%) Shipped within 7 - 12 working days

The story of the most significant biological breakthrough of the century - the discovery of the structure of DNA. 'It is a strange model and embodies several unusual features. However, since DNA is an unusual substance, we are not hesitant in being bold' By elucidating the structure of DNA, the molecule underlying all life, Francis Crick and James Watson revolutionised biochemistry. At the time, Watson was only 24. His uncompromisingly honest account of those heady days lifts the lid on the real world of great scientists, with their very human faults and foibles, their petty rivalries and driving ambition. Above all, he captures the extraordinary excitement of their desperate efforts to beat their rivals at King's College to the solution to one of the great enigmas of the life sciences.

Who We Are and How We Got Here - Ancient DNA and the new science of the human past (Paperback): David Reich Who We Are and How We Got Here - Ancient DNA and the new science of the human past (Paperback)
David Reich 1
R292 R197 Discovery Miles 1 970 Save R95 (33%) Shipped within 7 - 12 working days

The past few years have seen a revolution in our ability to map whole genome DNA from ancient humans. With the ancient DNA revolution, combined with rapid genome mapping of present human populations, has come remarkable insights into our past. This important new data has clarified and added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up some remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations existing today are mixes of ancient ones, as well as in many cases carrying a genetic component from Neanderthals, and, in some populations, Denisovans. David Reich, whose team has been at the forefront of these discoveries, explains what the genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial 'purity', or even deep and ancient divides between peoples. Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should celebrate our rich diversity, and recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?

The Tangled Tree - A Radical New History of Life (Hardcover, Edition): David Quammen The Tangled Tree - A Radical New History of Life (Hardcover, Edition)
David Quammen 1
R480 R334 Discovery Miles 3 340 Save R146 (30%) Shipped within 7 - 12 working days

Longlisted for the National Book Award for Nonfiction and A New York Times Notable Book of 2018. Our understanding of the `tree of life', with powerful implications for human genetics, human health and our own human nature, has recently completely changed. This book is about a new method of telling the story of life on earth - through molecular phylogenetics. It involves a fairly simple method - the reading of the deep history of life by looking at the variation in protein molecules found in living organisms. For instance, we now know that roughly eight per cent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection. In The Tangled Tree, acclaimed science writer David Quammen chronicles these discoveries through the lives of the researchers who made them - such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about `mosaic' creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. Quammen explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life - including where we humans fit into it. Thanks to new technologies, we now have the ability to alter even our genetic composition - through sideways insertions, as nature has long been doing. The Tangled Tree is a brilliant exploration of our transformed understanding of evolution and of life's history itself.

Unravelling the Double Helix - The Lost Heroes of DNA (Hardcover): Gareth Williams Unravelling the Double Helix - The Lost Heroes of DNA (Hardcover)
Gareth Williams 1
R487 R392 Discovery Miles 3 920 Save R95 (20%) Shipped within 7 - 12 working days

Unravelling the Double Helix covers the most colourful period in the history of DNA, from the discovery of 'nuclein' in the late 1860s to the landmark publication of James Watson's The Double Helix in 1968. These hundred years included the advent of the Nobel Prize, antibiotics, X-ray crystallography and the atom bomb as well as two devastating world wars - events which are strung along the narrative thread of DNA like beads on a necklace. The story of DNA is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar. The elucidation of the double helix was one of the most brilliant gems of twentieth-century science, but some of the scientists who played crucial roles have been airbrushed out of history. Others were plunged into darkness when the spotlight fell on James Watson, Francis Crick, Maurice Wilkins and Rosalind Franklin. Watson and Crick solved a magnificent mystery, but Gareth Williams shows that their contribution was to click into place the last few pieces of a gigantic jigsaw puzzle assembled over several decades.

Analyzing Network Data in Biology and Medicine - An Interdisciplinary Textbook for Biological, Medical and Computational... Analyzing Network Data in Biology and Medicine - An Interdisciplinary Textbook for Biological, Medical and Computational Scientists (Paperback)
Natasa Przulj
R1,056 R906 Discovery Miles 9 060 Save R150 (14%) Shipped within 7 - 12 working days

The increased and widespread availability of large network data resources in recent years has resulted in a growing need for effective methods for their analysis. The challenge is to detect patterns that provide a better understanding of the data. However, this is not a straightforward task because of the size of the data sets and the computer power required for the analysis. The solution is to devise methods for approximately answering the questions posed, and these methods will vary depending on the data sets under scrutiny. This cutting-edge text introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, before discussing the thought processes and creativity involved in the analysis of large-scale biological and medical data sets, using a wide range of real-life examples. Bringing together leading experts, this text provides an ideal introduction to and insight into the interdisciplinary field of network data analysis in biomedicine.

Blueprint - How DNA Makes Us Who We Are (Paperback): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Paperback)
Robert Plomin 1
R320 R252 Discovery Miles 2 520 Save R68 (21%) Shipped within 4 - 8 working days

One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

Francis Crick - Discoverer of the Genetic Code (Paperback): Matt Ridley Francis Crick - Discoverer of the Genetic Code (Paperback)
Matt Ridley
R231 R161 Discovery Miles 1 610 Save R70 (30%) Shipped within 7 - 12 working days

Acclaimed author Matt Ridley traces the colourful life of the man who discovered the structure of DNA, the building blocks of life. Building on a biographical tradition that can be traced back to Aubrey's `Brief Lives', Dr Johnson's `Lives of the Poets' and Lytton Strachey's `Eminent Victorians', this exciting and ground-breaking new series pairs great biographers, historians and novelists with iconic subjects, the writing bristling with original and distinctive points of view. On 28 February 1953, Francis Crick walked into the Eagle pub in Cambridge and announced that he and his American colleague James Watson `had found the secret of life'. In fact, they had indeed done so. That morning, Crick and Watson had worked out the structure of DNA (deoxyribonucleic acid). They had discovered its 'double helix' form, one which could replicate itself, confirming theories that it carried life's hereditary information. Matt Ridley's life of Crick begins with his birth in 1916 at the home of a shoe factory owner, his early explosive experiments at primary school and time developing torpedoes in the Navy. After his seismic DNA discovery, which won him the Nobel Prize before he'd even gained a PhD, the scientist's later work was rarely uncontroversial. From California, he proposed that life began when micro-organisms from another planet were dropped here by a spaceship sent to Earth, and maintained that the 'human soul' was entirely explicable in terms of brain activity. Matt Ridley's entertaining account traces the colourful and entirely original work behind one of mankind's greatest discoveries and displays the life of a scientist considered of the very first rank.

The Evolutionary Biology of Species (Paperback): Timothy Barraclough The Evolutionary Biology of Species (Paperback)
Timothy Barraclough
R806 Discovery Miles 8 060 Shipped within 7 - 12 working days

'Species' are central to understanding the origin and dynamics of biological diversity; explaining why lineages split into multiple distinct species is one of the main goals of evolutionary biology. However the existence of species is often taken for granted, and precisely what is meant by species and whether they really exist as a pattern of nature has rarely been modelled or critically tested. This novel book presents a synthetic overview of the evolutionary biology of species, describing what species are, how they form, the consequences of species boundaries and diversity for evolution, and patterns of species accumulation over time. The central thesis is that species represent more than just a unit of taxonomy; they are a model of how diversity is structured as well as how groups of related organisms evolve. The author adopts an intentionally broad approach, stepping back from the details to consider what species constitute, both theoretically and empirically, and how we detect them, drawing on a wealth of examples from microbes to multicellular organisms.

The Deeper Genome - Why there is more to the human genome than meets the eye (Paperback): John Parrington The Deeper Genome - Why there is more to the human genome than meets the eye (Paperback)
John Parrington
R322 R218 Discovery Miles 2 180 Save R104 (32%) Shipped within 7 - 12 working days

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'? Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

The Secret Life of Genes (Paperback): Derek Harvey The Secret Life of Genes (Paperback)
Derek Harvey
R285 R233 Discovery Miles 2 330 Save R52 (18%) Shipped within 4 - 8 working days

Genes have a huge impact on who we are, from defining us as humans, to governing how we behave. Whether controlling our cells or creating new forms of life, discover how DNA makes each of us unique. In The Secret Life of Genes, you'll learn all about the past, present and future of the human genome. Filled with colourful, graphic illustrations to help you to understand the world of genetics, from the basics to the most complex theories, this book brings the inner workings of the human body to life. Derek Harvey answers the biggest questions, from the nature of inheritance, evolution and reproduction, to how genes are arranged and how DNA is read. Take a trip through the history of the world's DNA and unlock the future of the field.

DNA Is You! - The Marvelous Science Behind Your One-of-a-Kind-ness (Hardcover): Beatrice the Biologist DNA Is You! - The Marvelous Science Behind Your One-of-a-Kind-ness (Hardcover)
Beatrice the Biologist
R268 R174 Discovery Miles 1 740 Save R94 (35%) Shipped within 7 - 12 working days

Learn all about how your DNA makes you who you are-an awesome, unique individual-in this fun and simple illustrated guide! Did you know your sense of purpose is determined by your genes? And that DNA determines your reaction to poison ivy, and maybe even your sex drive? In DNA Is You!, the author behind Beatrice the Biologist uses her trademark humor to break down the ins and outs of DNA to give you the low-down on each trait, one by one. She provides the answers to questions like: how dependent are traits on your parents' genes? Are they based on mutations or influenced by the environment? What kind of studies have been performed on genetics, and what have they discovered? Home DNA tests are more popular than ever, and DNA Is You! takes a look at the weird and wild scientific factors that can change your genes-like that dimples are dominant, how someone gets two different eye colors, and which genes determine whether or not you'll need glasses. Learn more about how you got to be who you are with DNA Is You! and understand yourself-and your family-a little bit better!

Rosalind Franklin (Paperback, New Ed): Brenda Maddox Rosalind Franklin (Paperback, New Ed)
Brenda Maddox 3
R259 R182 Discovery Miles 1 820 Save R77 (30%) Shipped within 7 - 12 working days

'A most moving and important biography, as well as an impressive account of a major event in the history of science'
Lewis Wolpert, 'Literary Review'

Although Rosalind Franklin took the crucial photograph of DNA revealing its double helix structure, her work was overlooked when, four years after her death, three men – Maurice Wilkins of King's College London, Francis Crick of the Cavendish Laboratory and James Watson of Cambridge – were awarded the Nobel Prize for the discovery of DNA.

In this compelling biography of Franklin, Brenda Maddox tells the story of a remarkably single-minded, forthright and tempestuous young woman, who at the age of fifteen decided she wanted to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

'Maddox is a dab hand at drawing a heroine out from behind the long shadows cast by men and her Franklin emerges as a determined, combative woman – a perfectionist who is plagued with self doubt'
Vanessa Thorpe, 'Observer'

'This magnificent biography gives a gripping yet nuanced account that resists the stock story-line of Franklin as the wronged heroine. What really happened is far more intriguing.'
Gail Vines, 'Independent'

'An exhilarating and vivid tale of scientific and personal politics at a time of rapid change in British science.'
Jane Gregory, 'New Scientist'

Alternative pre-mRNA Splicing - Theory and Protocols (Paperback): Stefan Stamm, Chris Smith, Reinhard Luhrmann Alternative pre-mRNA Splicing - Theory and Protocols (Paperback)
Stefan Stamm, Chris Smith, Reinhard Luhrmann
R2,374 R1,691 Discovery Miles 16 910 Save R683 (29%) Shipped within 7 - 13 working days

This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing in
twelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing.
A theoretical introduction and practical guide for molecular biologists, geneticists, clinicians and every researcher interested in alternative splicing.
Website: www.wiley-vch.de/home/splicing

Blueprint - How DNA Makes Us Who We Are (Hardcover): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Hardcover)
Robert Plomin 1
R467 R372 Discovery Miles 3 720 Save R95 (20%) Shipped within 7 - 12 working days

'A clear and engaging explanation of one of the hottest fields in science' Steven Pinker 'A hugely important book' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

Tag-based Next Generation Sequencing (Hardcover): Matthias Harbers, Guenter Kahl Tag-based Next Generation Sequencing (Hardcover)
Matthias Harbers, Guenter Kahl
R4,235 R2,976 Discovery Miles 29 760 Save R1,259 (30%) Shipped within 7 - 13 working days

Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequencing methods largely extended the use of tag-based approaches as the tag lengths perfectly match with the short read length of highly parallel sequencing reactions. Tag-based approaches will maintain their important role in life and biomedical science, because longer read lengths are often not required to obtain meaningful data for many applications. Whereas genome re-sequencing and de novo sequencing will benefit from ever more powerful sequencing methods, analytical applications can be performed by tag-based approaches, where the focus shifts from 'sequencing power' to better means of data analysis and visualization for common users. Today Next Generation Sequence data require powerful bioinformatics expertise that has to be converted into easy-to-use data analysis tools. The book's intention is to give an overview on recently developed tag-based approaches along with means of their data analysis together with introductions to Next-Generation Sequencing Methods, protocols and user guides to be an entry for scientists to tag-based approaches for Next Generation Sequencing.

A Primer of Molecular Population Genetics (Paperback): Asher D. Cutter A Primer of Molecular Population Genetics (Paperback)
Asher D. Cutter
R875 Discovery Miles 8 750 Shipped within 7 - 12 working days

What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

Bayesian Evolutionary Analysis with BEAST (Hardcover): Alexei J. Drummond, Remco R. Bouckaert Bayesian Evolutionary Analysis with BEAST (Hardcover)
Alexei J. Drummond, Remco R. Bouckaert
R931 Discovery Miles 9 310 Shipped within 7 - 12 working days

What are the models used in phylogenetic analysis and what exactly is involved in Bayesian evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you choose and apply these models, which parameterisations and priors make sense, and how can you diagnose Bayesian MCMC when things go wrong? These are just a few of the questions answered in this comprehensive overview of Bayesian approaches to phylogenetics. This practical guide: * Addresses the theoretical aspects of the field * Advises on how to prepare and perform phylogenetic analysis * Helps with interpreting analyses and visualisation of phylogenies * Describes the software architecture * Helps developing BEAST 2.2 extensions to allow these models to be extended further. With an accompanying website providing example files and tutorials (http://beast2.org/), this one-stop reference to applying the latest phylogenetic models in BEAST 2 will provide essential guidance for all users - from those using phylogenetic tools, to computational biologists and Bayesian statisticians.

Minicircle and Miniplasmid DNA Vectors - The Future of Non-viral and Viral Gene Transfer (Hardcover): Martin Schleef Minicircle and Miniplasmid DNA Vectors - The Future of Non-viral and Viral Gene Transfer (Hardcover)
Martin Schleef
R2,316 R1,633 Discovery Miles 16 330 Save R683 (29%) Shipped within 7 - 13 working days

This first title on the topic provides complete coverage, including the molecular basis, production and possible biomedical applications. Written by the most prominent academic researchers in the field as well as by researchers at one of the world's leading companies in industrial production of minicircle DNA, this practical book is aimed at everyone who is directly or indirectly involved in the development of gene therapies.

Post-Transcriptional Gene Regulation - RNA Processing in Eukaryotes (Hardcover): Jane Wu Post-Transcriptional Gene Regulation - RNA Processing in Eukaryotes (Hardcover)
Jane Wu
R2,571 R1,809 Discovery Miles 18 090 Save R762 (30%) Shipped within 7 - 13 working days

Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry.

Race Unmasked - Biology and Race in the Twentieth Century (Paperback): Michael Yudell Race Unmasked - Biology and Race in the Twentieth Century (Paperback)
Michael Yudell; Foreword by J. Craig Venter
R550 R427 Discovery Miles 4 270 Save R123 (22%) Shipped within 7 - 12 working days

Race, while drawn from the visual cues of human diversity, is an idea with a measurable past, an identifiable present, and an uncertain future. The concept of race has been at the center of both triumphs and tragedies in American history and has had a profound effect on the human experience. Race Unmasked revisits the origins of commonly held beliefs about the scientific nature of racial differences, examines the roots of the modern idea of race, and explains why race continues to generate controversy as a tool of classification even in our genomic age. Surveying the work of some of the twentieth century's most notable scientists, Race Unmasked reveals how genetics and related biological disciplines formed and preserved ideas of race and, at times, racism. A gripping history of science and scientists, Race Unmasked elucidates the limitations of a racial worldview and throws the contours of our current and evolving understanding of human diversity into sharp relief.

The Epigenetics Revolution - How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance... The Epigenetics Revolution - How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance (Paperback)
Nessa Carey 1
R261 R183 Discovery Miles 1 830 Save R78 (30%) Shipped within 7 - 12 working days

'A book that would have had Darwin swooning - anyone seriously interested in who we are and how we function should read this.' Guardian At the beginning of this century enormous progress had been made in genetics. The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

Who We Are and How We Got Here - Ancient DNA and the new science of the human past (Hardcover): David Reich Who We Are and How We Got Here - Ancient DNA and the new science of the human past (Hardcover)
David Reich 1
R527 R358 Discovery Miles 3 580 Save R169 (32%) Shipped within 7 - 12 working days

The past few years have witnessed a revolution in our ability to obtain DNA from ancient humans. This important new data has added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations living today are mixes of ancient ones, and often carry a genetic component from archaic humans. David Reich, whose team has been at the forefront of these discoveries, explains what genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial apurity.' Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?

Quantitative Genetics And Its Connections With Big Data And Sequenced Genomes (Hardcover): Charles J. Mode Quantitative Genetics And Its Connections With Big Data And Sequenced Genomes (Hardcover)
Charles J. Mode
R1,457 R1,088 Discovery Miles 10 880 Save R369 (25%) Shipped within 7 - 12 working days

The book gives an overview of developments in Quantitative Genetics and variance component analysis in an era of Big Data and Sequenced Genomes. It provides a detailed description of a direct method of estimation that will be a useful means of extracting information from a large set of data that was inconceivable 10 to 20 years ago.The book is a combination of a history of variance component analysis and a forward looking view as to how direct methods of estimation arise from the availability of big data sets and sequenced genomes of each individual in the sample.Many papers and books on quantitative genetics versions of the general linear model from statistics are useful for analyzing the data, using relatively small sets of data. In this book, new methods of direct estimation are introduced and analyzed that are appropriate for an era of big sets of data and sequences genomes. These direct methods of estimation are based on taking conditional expectations rather the methods of least squares that characterize many applications of the general linear model of statistics.

Quantitative Genetics And Its Connections With Big Data And Sequenced Genomes (Paperback): Charles J. Mode Quantitative Genetics And Its Connections With Big Data And Sequenced Genomes (Paperback)
Charles J. Mode
R788 R617 Discovery Miles 6 170 Save R171 (22%) Shipped within 7 - 12 working days

The book gives an overview of developments in Quantitative Genetics and variance component analysis in an era of Big Data and Sequenced Genomes. It provides a detailed description of a direct method of estimation that will be a useful means of extracting information from a large set of data that was inconceivable 10 to 20 years ago.The book is a combination of a history of variance component analysis and a forward looking view as to how direct methods of estimation arise from the availability of big data sets and sequenced genomes of each individual in the sample.Many papers and books on quantitative genetics versions of the general linear model from statistics are useful for analyzing the data, using relatively small sets of data. In this book, new methods of direct estimation are introduced and analyzed that are appropriate for an era of big sets of data and sequences genomes. These direct methods of estimation are based on taking conditional expectations rather the methods of least squares that characterize many applications of the general linear model of statistics.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Genomics: A Very Short Introduction
John M. Archibald Paperback R117 R104 Discovery Miles 1 040
Electrophoresis in Practice - A Guide to…
Reiner Westermeier Hardcover R2,589 R1,828 Discovery Miles 18 280
Unravelling the Double Helix - The Lost…
Gareth Williams Paperback  (1)
R325 R266 Discovery Miles 2 660
Biophysics of DNA
Alexander Vologodskii Hardcover R1,681 R1,577 Discovery Miles 15 770
The Material Gene - Gender, Race, and…
Kelly E. Happe Paperback R506 R434 Discovery Miles 4 340
A Brief History of Everyone Who Ever…
Adam Rutherford Paperback R318 R261 Discovery Miles 2 610
Wildlife DNA Analysis - Applications in…
Adrian Linacre, Shanan Tobe Hardcover R2,226 R1,991 Discovery Miles 19 910
Bioinformatics Data Skills…
Vince Buffalo Paperback R930 R614 Discovery Miles 6 140
Justice and Science - Trials and…
Paperback R542 Discovery Miles 5 420
Exploration and Analysis of DNA…
Dhammika Amaratunga, Javier Cabrera, … Hardcover R2,276 R1,604 Discovery Miles 16 040

 

Partners