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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA

Statistics and Data Analysis for Microarrays Using R and Bioconductor (Hardcover, 2nd edition): Sorin Draghici Statistics and Data Analysis for Microarrays Using R and Bioconductor (Hardcover, 2nd edition)
Sorin Draghici
R2,961 Discovery Miles 29 610 Ships in 9 - 15 working days

Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems. New to the Second EditionCompletely updated and double the size of its predecessor, this timely second edition replaces the commercial software with the open source R and Bioconductor environments. Fourteen new chapters cover such topics as the basic mechanisms of the cell, reliability and reproducibility issues in DNA microarrays, basic statistics and linear models in R, experiment design, multiple comparisons, quality control, data pre-processing and normalization, Gene Ontology analysis, pathway analysis, and machine learning techniques. Methods are illustrated with toy examples and real data and the R code for all routines is available on an accompanying downloadable resource. With all the necessary prerequisites included, this best-selling book guides students from very basic notions to advanced analysis techniques in R and Bioconductor. The first half of the text presents an overview of microarrays and the statistical elements that form the building blocks of any data analysis. The second half introduces the techniques most commonly used in the analysis of microarray data.

Modifications of Nuclear DNA and its Regulatory Proteins, Volume 101 (Hardcover, New): Xiaodong Cheng, Robert M. Blumenthal Modifications of Nuclear DNA and its Regulatory Proteins, Volume 101 (Hardcover, New)
Xiaodong Cheng, Robert M. Blumenthal
R4,051 Discovery Miles 40 510 Ships in 12 - 17 working days

DNA methylation is essential for the normal development and functioning of organisms. This volume discusses the latest developments in this very active field of research. It presents the evolution of DNA methylation, mammalian DNA methyltransferases, DNA methylation and demethlyation, DNA methylation and silencing and the role it plays in medicine including cancer.

* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Blueprint - How DNA Makes Us Who We Are (Paperback): Robert Plomin Blueprint - How DNA Makes Us Who We Are (Paperback)
Robert Plomin 1
R334 R271 Discovery Miles 2 710 Save R63 (19%) Ships in 9 - 15 working days

'Mind-blowing ... It is a hugely important book ... His story is crucial' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

Understanding DNA Ancestry (Hardcover): Sheldon Krimsky Understanding DNA Ancestry (Hardcover)
Sheldon Krimsky
R1,306 R1,078 Discovery Miles 10 780 Save R228 (17%) Ships in 12 - 17 working days

DNA ancestry companies generate revenues in the region of $1bn a year, and the company 23andMe is said to have sold 10 million DNA ancestry kits to date. Although evidently popular, the science behind how DNA ancestry tests work is mystifying and difficult for the general public to interpret and understand. In this accessible and engaging book, Sheldon Krimsky, a leading researcher, investigates the methods that different companies use for DNA ancestry testing. He also discusses what the tests are used for, from their application in criminal investigations to discovering missing relatives. With a lack of transparency from companies in sharing their data, absent validation of methods by independent scientists, and currently no agreed-upon standards of accuracy, this book also examines the ethical issues behind genetic genealogy testing, including concerns surrounding data privacy and security. It demystifies the art and science of DNA ancestry testing for the general reader.

Protein Interaction Networks, Volume 131 (Hardcover): Rossen Donev Protein Interaction Networks, Volume 131 (Hardcover)
Rossen Donev
R3,834 Discovery Miles 38 340 Ships in 12 - 17 working days

Protein Interaction Networks, Volume 131 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Nuclear Mechanics and Genome Regulation, Volume 98 (Hardcover, 101st edition): G.V. Shivashankar Nuclear Mechanics and Genome Regulation, Volume 98 (Hardcover, 101st edition)
G.V. Shivashankar
R4,055 Discovery Miles 40 550 Ships in 12 - 17 working days

In recent years new discoveries have made this an exciting and important field of research. This comprehensive volume presents comprehensive chapters and detailed background information for researchers working with in the field of Nuclear Mechanics and Genome Regulation.

* Both classic and state-of-the-art methods readily adaptable and designed to last the test of time * Relevant to clinicians and scientists working in a wide range of fields

Structural Genomics, Part B, Volume 76 (Hardcover): Andrzej Joachimiak Structural Genomics, Part B, Volume 76 (Hardcover)
Andrzej Joachimiak
R3,543 Discovery Miles 35 430 Ships in 12 - 17 working days

Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.
While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale.
Key Features
*Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy
* Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission

DNA and Biotechnology (Hardcover, 3rd edition): Molly Fitzgerald-Hayes, Frieda Reichsman DNA and Biotechnology (Hardcover, 3rd edition)
Molly Fitzgerald-Hayes, Frieda Reichsman
R1,967 Discovery Miles 19 670 Ships in 12 - 17 working days

Appropriate for a wide range of disciplines, from biology to non-biology, law and nursing majors, "DNA and Biotechnology" uses a straightforward and comprehensive writing style that gives the educated layperson a survey of DNA by presenting a brief history of genetics, a clear outline of techniques that are in use, and highlights of breakthroughs in hot topic scientific discoveries.

Engaging and straightforward scientific writing style Comprehensive forensics chapter Parallel Pedagogic material designed to help both readers and teachers. Highlights in the latest scientific discoveries Outstanding full-color illustration that walk reader through complex concepts

Effects of Genome Structure and Sequence on the Generation of Variation and Evolution (Paperback): LH Caporale Effects of Genome Structure and Sequence on the Generation of Variation and Evolution (Paperback)
LH Caporale
R3,077 Discovery Miles 30 770 Ships in 12 - 17 working days

The structure of DNA varies along its sequence, which can lead to sequence-dependent variations in the fidelity of DNA copying and repair. And because the probability of distinct classes of mutations varies along a DNA sequence, variation that affects fitness will have evolutionary implications, as selection acts on heritable variation.

This Annals volume brings together a broad interdisciplinary group of researchers to explore the impact of increasing understanding of DNA structure, repair, replication, and organization on interrelated subjects ranging from evolution, to dependence of the effect of mutagens on environmental and sequence context, to noncanonical forms of information representation in genomes.

NOTE: "Annals" volumes are avaialble for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http: //ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632

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Genomics (WIRED guides) - How Genome Sequencing Will Change Our Lives (Paperback): Rachael Pells, Wired Genomics (WIRED guides) - How Genome Sequencing Will Change Our Lives (Paperback)
Rachael Pells, Wired
R215 R172 Discovery Miles 1 720 Save R43 (20%) Ships in 5 - 10 working days

Genome sequencing is one of the most exciting scientific breakthroughs of the past thirty years. But what precisely does it involve and how is it developing? In this brilliantly wide-ranging, one-stop guide WIRED journalist Rachael Pells explains the science behind genomics. She analyses its practical applications in medical diagnosis and the treatment of conditions that range from cancer to severe allergic reactions to cystic fibrosis. She considers its potential to help with advances in agriculture and environmental science. She explores the ethics of genetic modification and the dangers involved when humans 'play God'. And she addresses the fundamental question: to what extent will future advances transform human longevity and the quality of life.

RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways, Volume 449 (Hardcover): Lynne E.... RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways, Volume 449 (Hardcover)
Lynne E. Maquat, Megerditch Kiledjian
R4,368 Discovery Miles 43 680 Ships in 12 - 17 working days

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.
* Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway
* Expert researchers introduce the most advanced technologies and techniques
* Offers step-by-step lab instructions, including necessary equipment and reagents

Genomics in Biosecurity - Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts (Paperback):... Genomics in Biosecurity - Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts (Paperback)
Manousos E. Kambouris
R3,043 Discovery Miles 30 430 Ships in 12 - 17 working days

Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts, in the Translational and Applied Genomics series, explains in definite and practical terms the applicability of genomic technologies in every aspect of biosecurity, from emergent diagnostics to bioterrorism, agroterrorism, next generation biowarfare, biosurveillance and risk assessment. This book offers an integrated discussion of genomics and GCBR (global catastrophic biological risks) events, considering both basic aspects of biosecurity genomics and application of genomic technologies to drive new solutions. Readers will find evidence-based strategies to apply genomics in disease and pathogen monitoring and diagnosis, and more. Social aspects of GCBR events and genomic biosecurity, such as issues of terrorism, policy ethics, and practice, are also considered in-depth.

Protein Design and Structure, Volume 130 (Hardcover): Rossen Donev Protein Design and Structure, Volume 130 (Hardcover)
Rossen Donev
R3,864 Discovery Miles 38 640 Ships in 12 - 17 working days

Protein Design and Structure, Volume 130 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

R Programming for Bioinformatics (Hardcover): Robert Gentleman R Programming for Bioinformatics (Hardcover)
Robert Gentleman
R2,746 Discovery Miles 27 460 Ships in 12 - 17 working days

Due to its data handling and modeling capabilities as well as its flexibility, R is becoming the most widely used software in bioinformatics. R Programming for Bioinformatics explores the programming skills needed to use this software tool for the solution of bioinformatics and computational biology problems. Drawing on the author's first-hand experiences as an expert in R, the book begins with coverage on the general properties of the R language, several unique programming aspects of R, and object-oriented programming in R. It presents methods for data input and output as well as database interactions. The author also examines different facets of string handling and manipulations, discusses the interfacing of R with other languages, and describes how to write software packages. He concludes with a discussion on the debugging and profiling of R code. With numerous examples and exercises, this practical guide focuses on developing R programming skills in order to tackle problems encountered in bioinformatics and computational biology.

New High Throughput Technologies for DNA Sequencing and Genomics, Volume 2 (Hardcover, 2nd edition): Keith R. Mitchelson New High Throughput Technologies for DNA Sequencing and Genomics, Volume 2 (Hardcover, 2nd edition)
Keith R. Mitchelson
R5,238 Discovery Miles 52 380 Ships in 12 - 17 working days

Since the independent invention of DNA sequencing by Sanger and by Gilbert 30 years ago, it has grown from a small scale technique capable of reading several kilobase-pair of sequence per day into today's multibillion dollar industry. This growth has spurred the development of new sequencing technologies that do not involve either electrophoresis or Sanger sequencing chemistries. Sequencing by Synthesis (SBS) involves multiple parallel micro-sequencing addition events occurring on a surface, where data from each round is detected by imaging.
New High Throughput Technologies for DNA Sequencing and Genomics is the second volume in the Perspectives in Bioanalysis series, which looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century.
Reviews of complementary developments in Sanger and SBS sequencing chemistries, capillary electrophoresis and microdevice integration, MS sequencing and applications set the framework for the book.
* 'Hot Topic' with DNA sequencing continuing as a major research activity in many areas of life science and medicine.
* Bringing together new developments in DNA sequencing technology
* Reviewing issues relevant to the new applications used

DNA Microarrays, Part A: Array Platforms and Wet-Bench Protocols, Volume 410 (Hardcover, 410th edition): Alan R. Kimmel, Brian... DNA Microarrays, Part A: Array Platforms and Wet-Bench Protocols, Volume 410 (Hardcover, 410th edition)
Alan R. Kimmel, Brian Oliver
R4,365 Discovery Miles 43 650 Ships in 12 - 17 working days

Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results.
Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations.
Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician.
- Provides an overview of platforms
- Includes experimental design and wet bench protocols
- Presents statistical and data analysis methods, array databases, data visualization and meta analysis

DNA Repair, Part A, Volume 408 (Hardcover, 408th edition): Judith L. Campbell, Paul Modrich DNA Repair, Part A, Volume 408 (Hardcover, 408th edition)
Judith L. Campbell, Paul Modrich
R4,375 Discovery Miles 43 750 Ships in 12 - 17 working days

This volume provides detailed coverage of modern methods for molecular analysis of enzymes and enzyme systems that function in the maintenance of genome integrity. Coverage areas include base excision repair, nucleotide excision repair, translesion DNA polymerases, mismatch repair, genetic recombination, and double strand break repair.
*A laboratory standard for more than 40 years
*Over 400 volumes strong
*Also available on ScienceDirect
*Part A of a 2-part series

DNA Repair, Part B, Volume 409 (Hardcover, 409th edition): Judith L. Campbell, Paul Modrich DNA Repair, Part B, Volume 409 (Hardcover, 409th edition)
Judith L. Campbell, Paul Modrich
R4,377 Discovery Miles 43 770 Ships in 12 - 17 working days

This volume emphasizes the intracellular consequences of DNA damage, describing procedures for analysis of checkpoint responses, DNA repair in vivo, replication fork encounter of DNA damage, as well as biological methods for analysis of mutation production and chromosome rearrangements. It also describes molecular methods for analysis of a number of genome maintenance activities including DNA ligases, helicases, and single-strand binding proteins.
*Part B of a 2-part series
*Addresses DNA maintenance enzymes
*Discusses damage signaling
*Presents "In vivo" analysis of DNA repair
*Covers mutation and chromosome rearrangements

The Human Genome in Health and Disease - A Story of Four Letters (Hardcover): Tore Samuelsson The Human Genome in Health and Disease - A Story of Four Letters (Hardcover)
Tore Samuelsson
R3,951 Discovery Miles 39 510 Ships in 12 - 17 working days

The human genome is a linear sequence of roughly 3 billion bases and information regarding this genome is accumulating at an astonishing rate. Inspired by these advances, The Human Genome in Health and Disease: A Story of Four Letters explores the intimate link between sequence information and biological function. A range of sequence-based functional units of the genome are discussed and illustrated with inherited disorders and cancer. In addition, the book considers valuable medical applications related to human genome sequencing, such as gene therapy methods and the identification of causative mutations in rare genetic disorders. The primary audiences of the book are students of genetics, biology, medicine, molecular biology and bioinformatics. Richly illustrated with review questions provided for each chapter, the book helps students without previous studies of genetics and molecular biology. It may also be of benefit for advanced non-academics, which in the era of personal genomics, want to learn more about their genome. Key selling features: Molecular sequence perspective, explaining the relationship between DNA sequence motifs and biological function Aids in understanding the functional impact of mutations and genetic variants Material presented at basic level, making it accessible to students without previous studies of genetics and molecular biology Richly illustrated with questions provided to each chapter

DNA Microarrays for Biomedical Research - Methods and Protocols (Hardcover, 2009 ed.): Martin Dufva DNA Microarrays for Biomedical Research - Methods and Protocols (Hardcover, 2009 ed.)
Martin Dufva
R2,956 Discovery Miles 29 560 Ships in 10 - 15 working days

DNA microarray technology has revolutionized research in the past decade. Initially an application for mRNA expression studies, the technology now has spread to other applications such as comparative genomic hybridization, SNP and mutation analysis. In DNA Microarrays for Biomedical Research: Methods and Protocols, experts explore these now commonly used applications, addressing probe design strategies, fabrication issues and providing practical examples of detailed methods for generation of high quality DNA microarray data. Chapters incorporate information on some of the largest providers of microarray, including Affymetrix, Ilumina and Agilent, and their use on a variety of applications. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Authoritative and highly practical, DNA Microarrays for Biomedical Research: Methods and Protocols presents a variety of protocols which can be easily reproduced, allowing researchers to gain surprising insight into the complex world of DNA microarray technology.

DNA Repair and Replication, Volume 69 (Hardcover): Wei Yang DNA Repair and Replication, Volume 69 (Hardcover)
Wei Yang
R3,733 Discovery Miles 37 330 Ships in 12 - 17 working days

DNA Repair and Replication contains an up-to-date review of general principles of DNA replication and an overview of the multiple pathways involved in DNA repair. Specific DNA repair pathways, including base-excision repair, light-dependent direct reversal of UV-damage, nucleotide-excision repair, transcription-coupled repair, double-strand break repair, and mismatch repair, are each discussed in separate chapters.
Selected Contents:
-Base Excision Repair
-Eukaryotic DNA Mismatch Repair
-Double Strand Break Repair
-Functions of DNA Polymerases
-Somatic Hypermutation: A Mutational Panacea

The Maize Genome (Hardcover, 1st ed. 2018): Jeffrey Bennetzen, Sherry Flint-Garcia, Candice Hirsch, Roberto Tuberosa The Maize Genome (Hardcover, 1st ed. 2018)
Jeffrey Bennetzen, Sherry Flint-Garcia, Candice Hirsch, Roberto Tuberosa
R6,126 Discovery Miles 61 260 Ships in 12 - 17 working days

This book discusses advances in our understanding of the structure and function of the maize genome since publication of the original B73 reference genome in 2009, and the progress in translating this knowledge into basic biology and trait improvement. Maize is an extremely important crop, providing a large proportion of the world's human caloric intake and animal feed, and serving as a model species for basic and applied research. The exceptionally high level of genetic diversity within maize presents opportunities and challenges in all aspects of maize genetics, from sequencing and genotyping to linking genotypes to phenotypes. Topics covered in this timely book range from (i) genome sequencing and genotyping techniques, (ii) genome features such as centromeres and epigenetic regulation, (iii) tools and resources available for trait genomics, to (iv) applications of allele mining and genomics-assisted breeding. This book is a valuable resource for researchers and students interested in maize genetics and genomics.

Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics - Perinatal and Reproductive Genetics... Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics - Perinatal and Reproductive Genetics (Hardcover, 7th edition)
Reed E. Pyeritz, Bruce R. Korf, Wayne W. Grody
R2,622 Discovery Miles 26 220 Ships in 12 - 17 working days

Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Perinatal and Reproductive Genetics, Seventh Edition includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies in this growing field. The book is ideal for medical students, residents, physicians and researchers involved in the care of patients with genetic conditions. This comprehensive, yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. Chapters from leading international researchers and clinicians focus on topics ranging from single gene testing to whole genome sequencing, whole exome sequencing, gene therapy, genome editing approaches, FDA regulations on genomic testing and therapeutics, and ethical aspects of employing genomic technologies.

DNA for Defense Attorneys (Hardcover): Rohan Cassinelli DNA for Defense Attorneys (Hardcover)
Rohan Cassinelli
R4,124 Discovery Miles 41 240 Ships in 12 - 17 working days

Deoxyribonucleic acid, or DNA, is the fundamental building block for an individual's entire genetic make-up. DNA is a powerful tool for law enforcement investigations because each person's DNA is different from that of every other individual (except for identical twins). DNA can be extracted from a number of sources, such as hair, bone, teeth, saliva, and blood. As early as the 1980s, states began enacting laws that required collecting DNA samples from offenders convicted of certain sexual and other violent crimes. The samples were then analysed and their profiles entered into state databases. Meanwhile, the FBI laboratory convened a working group of federal, state, and local forensic scientists to establish guidelines for the use of forensic DNA analysis in laboratories. This book provides an overview of how DNA is used to investigate crimes and help protect the innocent. It reviews current statutory law on collecting DNA samples, sharing DNA profiles, and providing access to post-conviction DNA testing.

Epigenetics of Exercise and Sports, Volume 25 - Concepts, Methods, and Current Research (Paperback): Stuart Raleigh Epigenetics of Exercise and Sports, Volume 25 - Concepts, Methods, and Current Research (Paperback)
Stuart Raleigh
R3,596 Discovery Miles 35 960 Ships in 12 - 17 working days

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.

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