Recombinant Gene Expression - Reviews and Protocols (Hardcover, 2nd ed. 2004)

Since newly created beings are often perceived as either wholly good or bad, the genetic alteration of living cells impacts directly on a symbolic meaning deeply imbedded in every culture. During the earlier years of gene expression research, te- nological applications were confined mainly to academic and industrial laboratories, and were perceived as highly beneficial since molecules that were previously unable to be separated or synthesized became accessible as therapeutic agents. Such were the success stories of hormones, antibodies, and vaccines produced in the bacterium Escherichia coli. Originally this bacterium gained fame among humans for being an unwanted host in the intestine, or worse yet, for being occasionally dangerous and pathogenic. H- ever, it was easily identified in contaminated waters during the 19th century, thus becoming a clear indicator of water pollution by human feces. Tamed, cultivated, and easily maintained in laboratories, its fast growth rate and metabolic capacity to adjust to changing environments fascinated the minds of scientists who studied and modeled such complex phenomena as growth, evolution, genetic exchange, infection, survival, adaptation, and further on-gene expression. Although at the lower end of the complexity scale, this microbe became a very successful model system and a key player in the fantastic revolution kindled by the birth of recombinant DNA technology.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 267
Release date:	July 2004
First published:	2004
Editors:	Paulina Balbas • Argelia Lorence
Dimensions:	235 x 155 x 36mm (L x W x T)
Format:	Hardcover
Pages:	508
Edition:	2nd ed. 2004
ISBN-13:	978-1-58829-262-9
Categories:	Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA Promotions
LSN:	1-58829-262-2
Barcode:	9781588292629

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