0
Your cart

Your cart is empty

Browse All departments
Price
  • R50 - R100 (1)
  • R100 - R250 (35)
  • R250 - R500 (68)
  • R500+ (776)
  • -
Status
Format
Author / Contributor
Publisher

Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA

Handbook of RNA Biochemistry - 2 Volume Set (Hardcover, 2nd Edition): Roland K. Hartmann, Albrecht Bindereif, Astrid Schon,... Handbook of RNA Biochemistry - 2 Volume Set (Hardcover, 2nd Edition)
Roland K. Hartmann, Albrecht Bindereif, Astrid Schon, Eric Westhof
R7,316 R6,696 Discovery Miles 66 960 Save R620 (8%) Shipped within 7 - 12 working days

The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.

DNA and Tissue Banking for Biodiversity and Conservation - Theory, Practice and Uses (Paperback): Vincent Savolainen, Martyn P.... DNA and Tissue Banking for Biodiversity and Conservation - Theory, Practice and Uses (Paperback)
Vincent Savolainen, Martyn P. Powell, Kate Davis, Gail Reeves, Angelique Corthals
R898 R701 Discovery Miles 7 010 Save R197 (22%) Shipped within 7 - 12 working days

DNA and Tissue Banking provides a practical and legislative framework covering uses of DNA, requirements of the Convention on Biological Diversity and CITES, model legal documents, practical guidelines for setting up DNA and tissue banks and worldwide case studies. Essential reading for all who wish to understand the application of genetic technologies to conservation.

The Molecular Invasion (Paperback): Critical Art Ensemble The Molecular Invasion (Paperback)
Critical Art Ensemble
R205 R156 Discovery Miles 1 560 Save R49 (24%) Shipped within 7 - 12 working days

Womb transplant babies 'within three years.''If implantable wombs become a reality in humans, they need not be confined to women. Some men might also be keen.' Guardian, July 2003Having exhausted the possibilities for geographic colonial expansion, as well as reaching the fiscal limitations of virtual space, capital is now concentrated on exploiting a new frontier -- organic molecular space. Critical Art Ensemble began mapping this development in Flesh Machine (Autonomedia, 1998) by examining the use of reproductive technologies and their promise for achieving an intensified degree of control over worker and citizen. The Molecular Invasion acts as a companion to this first book by mapping the politics of transgenics, and offering a model for the creation of a contestational biology, as well as providing direct interventionist tactics for the disruption of this new assault on the organic realm. The Molecular Invasion is an indispensable user's guide for anyone interested in the critical thinking and practice of biotech as a social, scientific, and political phenomenon.

Plant Genome Diversity Volume 2 - Physical Structure, Behaviour and Evolution of Plant Genomes (Hardcover, 2012): Johann... Plant Genome Diversity Volume 2 - Physical Structure, Behaviour and Evolution of Plant Genomes (Hardcover, 2012)
Johann Greilhuber, Jaroslav Dolezel, Jonathan F. Wendel; Edited by (editors-in-chief) Ilia J. Leitch
R4,870 R4,119 Discovery Miles 41 190 Save R751 (15%) Shipped within 7 - 12 working days

This second of two volumes on Plant Genome Diversity provides, in 20 chapters, insights into the structural evolution of plant genomes with all its variations. Starting with an outline of plant phylogeny and its reconstruction, the second part of the volume describes the architecture and dynamics of the plant cell nucleus, the third examines the evolution and diversity of the karyotype in various lineages, including angiosperms, gymnosperms and monilophytes. The fourth part presents the mechanisms of polyploidization and its biological consequences and significance for land plant evolution. The fifth part deals with genome size evolution and its biological significance. Together with Volume I, this comprehensive book on the plant genome is intended for students and professionals in all fields of plant science, offering as it does a convenient entry into a burgeoning literature in a fast-moving field.

An Introduction to Molecular Evolution and Phylogenetics (Paperback, 2nd Revised edition): Lindell Bromham An Introduction to Molecular Evolution and Phylogenetics (Paperback, 2nd Revised edition)
Lindell Bromham
R1,014 Discovery Miles 10 140 Shipped within 7 - 12 working days

DNA can be extracted and sequenced from a diverse range of biological samples, providing a vast amount of information about evolution and ecology. The analysis of DNA sequences contributes to evolutionary biology at all levels, from dating the origin of the biological kingdoms to untangling family relationships. An Introduction to Molecular Evolution and Phylogenetics presents the fundamental concepts and intellectual tools you need to understand how the genome records information about evolutionary past and processes, how that information can be "read", and what kinds of questions we can use that information to answer. Starting with evolutionary principles, and illustrated throughout with biological examples, it is the perfect starting point on the journey to an understanding of the way molecular data is used in modern biology. Online Resource Centre The Online Resource Centre features: For registered adopters of the book: - Class plans for one-hour hands-on sessions associated with each chapter - Figures from the textbook to view and download

The Peanut Genome (Hardcover, 1st ed. 2017): Rajeev K Varshney, Manish K. Pandey, Naveen Puppala The Peanut Genome (Hardcover, 1st ed. 2017)
Rajeev K Varshney, Manish K. Pandey, Naveen Puppala
R2,666 R2,379 Discovery Miles 23 790 Save R287 (11%) Shipped within 7 - 12 working days

This book presents the current state of the art in peanut genomics, focusing particularly on the latest genomic findings, tools and strategies employed in genome sequencing, transcriptomes and analysis, availability of public and private genomic resources, and ways to maximize the use of this information in peanut breeding programs. Further, it demonstrates how advances in plant genomics can be used to improve crop breeding. The peanut or groundnut (Arachis hypogaea L. Millsp) is a globally important grain legume and oilseed crop, cultivated in over 100 countries and consumed in the form of roasted seeds, oil and confectionary in nearly every country on Earth. The peanut contributes towards achieving food and nutritional security, in addition to financial security through income generation; as such, it is also vital to the livelihood of the poor in the developing world. There have been significant advances in peanut research, especially in the last five years, including sequencing the genome of both diploid progenitors, and the availability of tremendous transcriptome resources, large-scale genomic variations that can be used as genetic markers, genetic populations (bi- and multiparent populations and germplasm sets), marker-trait associations and molecular breeding products. The immediate availability of the genome sequence for tetraploid cultivated peanuts is the most essential genomic resource for achieving a deeper understanding of peanut traits and their use in breeding programs.

Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics - Foundations (Hardcover, 7th edition): Reed... Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics - Foundations (Hardcover, 7th edition)
Reed E. Pyeritz, Bruce R. Korf, Wayne W. Grody
R2,173 R2,020 Discovery Miles 20 200 Save R153 (7%) Shipped within 7 - 12 working days

For decades, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With detailed coverage in contributions from over 250 of the world's most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. This volume, Foundations, summarizes basic theories, concepts, research areas, and the history of medical genetics, providing a contextual framework for integrating genetics into medical practice. In this new edition, clinically oriented information is supported by full-color images and expanded sections on the foundations of genetic analytics, next generation sequencing, and therapeutics. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for the health professionals and researchers.

Dictionary of DNA and Genome Technology (Hardcover, 3rd Edition): Paul Singleton Dictionary of DNA and Genome Technology (Hardcover, 3rd Edition)
Paul Singleton
R2,331 R1,649 Discovery Miles 16 490 Save R682 (29%) Shipped within 7 - 13 working days

DNA technology is evolving rapidly, with new methods and a fast-growing vocabulary. This unique dictionary offers current, detailed and accessible information on DNA technology to lecturers, researchers and students throughout the biomedical and related sciences.

The third edition is a major update, with over 3000 references from mainstream journals and data from the very latest research - going well beyond the remit of most science dictionaries. It provides clear explanations of terms, techniques, and tests, including commercial systems, with detailed coverage of many important procedures and methods, and includes essay-style entries on many major topics to assist newcomers to the field. It covers topics relevant to medicine (diagnosis, genetic disorders, gene therapy); veterinary science; biotechnology; biochemistry; pharmaceutical science/drug development; molecular biology; microbiology; epidemiology; genomics; environmental science; plant science/agriculture; taxonomy; and forensic science.

The Radish Genome (Hardcover, 1st ed. 2017): Takeshi Nishio, Hiroyasu Kitashiba The Radish Genome (Hardcover, 1st ed. 2017)
Takeshi Nishio, Hiroyasu Kitashiba
R3,409 R2,685 Discovery Miles 26 850 Save R724 (21%) Shipped within 7 - 12 working days

This book summarizes the latest information and the status quo of radish genome studies to stimulate innovations and improvements in breeding techniques and to promote further advances in the field. Radish (Raphanus sativus) is a member of the Brassicaceae family and is cultivated worldwide. Its varieties have been diversified in terms of size, shape, and the color of their roots and bio-components. Thanks to the development of high-throughput molecular techniques using next generation sequencers, complete genomes of cultivated and wild radish plants have been sequenced and published with annotations of predicted genes and single nucleotide polymorphism (SNP) information between radish cultivars and accessions. These, together with the construction of a high-density genetic map of radish and profiling of expression sequences in radish organs, have accelerated genetic studies, such as the identification of genes or loci associated with root development, pungent components, and plant disease resistance. Providing an overview of these advances, this book is a valuable resource for scientists involved in plant genetic research and crop breeding.

Effects of Genome Structure and Sequence on the Generation of Variation and Evolution, Volume 1267 (Paperback): Lynn Helena... Effects of Genome Structure and Sequence on the Generation of Variation and Evolution, Volume 1267 (Paperback)
Lynn Helena Caporale
R2,456 R1,724 Discovery Miles 17 240 Save R732 (30%) Shipped within 7 - 13 working days

The structure of DNA varies along its sequence, which can lead to sequence-dependent variations in the fidelity of DNA copying and repair. And because the probability of distinct classes of mutations varies along a DNA sequence, variation that affects fitness will have evolutionary implications, as selection acts on heritable variation.

This Annals volume brings together a broad interdisciplinary group of researchers to explore the impact of increasing understanding of DNA structure, repair, replication, and organization on interrelated subjects ranging from evolution, to dependence of the effect of mutagens on environmental and sequence context, to noncanonical forms of information representation in genomes.

NOTE: "Annals" volumes are avaialble for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http: //ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to "Annals "online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Joun.aspx for more information about becoming a member.

The Least Likely Man - Marshall Nirenberg and the Discovery of the Genetic Code (Paperback): Franklin H. Portugal The Least Likely Man - Marshall Nirenberg and the Discovery of the Genetic Code (Paperback)
Franklin H. Portugal
R322 R259 Discovery Miles 2 590 Save R63 (20%) Shipped within 7 - 12 working days

How unassuming government researcher Marshall Nirenberg beat James Watson, Francis Crick, and other world-famous scientists in the race to discover the genetic code. The genetic code is the Rosetta Stone by which we interpret the 3.3 billion letters of human DNA, the alphabet of life, and the discovery of the code has had an immeasurable impact on science and society. In 1968, Marshall Nirenberg, an unassuming government scientist working at the National Institutes of Health, shared the Nobel Prize for cracking the genetic code. He was the least likely man to make such an earth-shaking discovery, and yet he had gotten there before such members of the scientific elite as James Watson and Francis Crick. How did Nirenberg do it, and why is he so little known? In The Least Likely Man, Franklin Portugal tells the fascinating life story of a famous scientist that most of us have never heard of. Nirenberg did not have a particularly brilliant undergraduate or graduate career. After being hired as a researcher at the NIH, he quietly explored how cells make proteins. Meanwhile, Watson, Crick, and eighteen other leading scientists had formed the "RNA Tie Club" (named after the distinctive ties they wore, each decorated with one of twenty amino acid designs), intending to claim credit for the discovery of the genetic code before they had even worked out the details. They were surprised, and displeased, when Nirenberg announced his preliminary findings of a genetic code at an international meeting in Moscow in 1961. Drawing on Nirenberg's "lab diaries," Portugal offers an engaging and accessible account of Nirenberg's experimental approach, describes counterclaims by Crick, Watson, and Sidney Brenner, and traces Nirenberg's later switch to an entirely new, even more challenging field. Having won the Nobel for his work on the genetic code, Nirenberg moved on to the next frontier of biological research: how the brain works.

Agricultural Bioinformatics (Hardcover, 2014 ed.): PB Kavi Kishor, Rajib Bandyopadhyay, Prashanth Suravajhala Agricultural Bioinformatics (Hardcover, 2014 ed.)
PB Kavi Kishor, Rajib Bandyopadhyay, Prashanth Suravajhala
R4,142 R3,340 Discovery Miles 33 400 Save R802 (19%) Shipped within 7 - 12 working days

A common approach to understanding the functional repertoire of a genome is through functional genomics. With systems biology burgeoning, bioinformatics has grown to a larger extent for plant genomes where several applications in the form of protein-protein interactions (PPI) are used to predict the function of proteins. With plant genes evolutionarily conserved, the science of bioinformatics in agriculture has caught interest with myriad of applications taken from bench side to in silico studies. A multitude of technologies in the form of gene analysis, biochemical pathways and molecular techniques have been exploited to an extent that they consume less time and have been cost-effective to use. As genomes are being sequenced, there is an increased amount of expression data being generated from time to time matching the need to link the expression profiles and phenotypic variation to the underlying genomic variation. This would allow us to identify candidate genes and understand the molecular basis/phenotypic variation of traits. While many bioinformatics methods like expression and whole genome sequence data of organisms in biological databases have been used in plants, we felt a common reference showcasing the reviews for such analysis is wanting. We envisage that this dearth would be facilitated in the form of this Springer book on Agricultural Bioinformatics. We thank all the authors and the publishers Springer, Germany for providing us an opportunity to review the bioinformatics works that the authors have carried in the recent past and hope the readers would find this book attention grabbing.

Clinical Genome Sequencing - Psychological Considerations (Paperback): Aad Tibben, Barbara B. Biesecker Clinical Genome Sequencing - Psychological Considerations (Paperback)
Aad Tibben, Barbara B. Biesecker
R1,539 R1,436 Discovery Miles 14 360 Save R103 (7%) Shipped within 7 - 12 working days

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.

Gene Expression and Its Discontents - The Social Production of Chronic Disease (Hardcover, 2nd ed. 2016): Rodrick Wallace,... Gene Expression and Its Discontents - The Social Production of Chronic Disease (Hardcover, 2nd ed. 2016)
Rodrick Wallace, Deborah Wallace
R2,915 R2,640 Discovery Miles 26 400 Save R275 (9%) Shipped within 7 - 12 working days

This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer's disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the population level in the face of persistent individual and community stress. Drugs powerful enough to affect deleterious epigenetic programming will likely have side effects leading to shortened lifespan. Addressing chronic conditions and developmental disorders requires significant large-scale changes in public policy and resource allocation.

Handbook of Epigenetics - The New Molecular and Medical Genetics (Hardcover, 2nd edition): Trygve Tollefsbol Handbook of Epigenetics - The New Molecular and Medical Genetics (Hardcover, 2nd edition)
Trygve Tollefsbol
R3,951 R2,821 Discovery Miles 28 210 Save R1,130 (29%) Shipped within 7 - 12 working days

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders.

Synthetic mRNA - Production, Introduction Into Cells, and Physiological Consequences (Hardcover, 1st ed. 2016): Robert E. Rhoads Synthetic mRNA - Production, Introduction Into Cells, and Physiological Consequences (Hardcover, 1st ed. 2016)
Robert E. Rhoads
R3,076 R2,788 Discovery Miles 27 880 Save R288 (9%) Shipped within 7 - 12 working days

This volume presents detailed laboratory protocols for in vitro synthesis of mRNA with favorable properties, its introduction into cells by a variety of techniques, and the measurement of physiological and clinical consequences such as protein replacement and cancer immunotherapy. Synthetic techniques are described for structural features in mRNA that provide investigational tools such as fluorescence emission, click chemistry, photo-chemical crosslinking, and that produce mRNA with increased stability in the cell, increased translational efficiency, and reduced activation of the innate immune response. Protocols are described for clinical applications such as large-scale transfection of dendritic cells, production of GMP-grade mRNA, redirecting T cell specificity, and use of molecular adjuvants for RNA vaccines. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Synthetic mRNA: Production, Introduction into Cells, and Physiological Consequences is a valuable and cutting-edge resource for both laboratory investigators and clinicians interested in this powerful and rapidly evolving technology.

DNA for Defense Attorneys (Hardcover): Rohan Cassinelli DNA for Defense Attorneys (Hardcover)
Rohan Cassinelli
R3,162 R2,392 Discovery Miles 23 920 Save R770 (24%) Shipped within 7 - 12 working days

Deoxyribonucleic acid, or DNA, is the fundamental building block for an individual's entire genetic make-up. DNA is a powerful tool for law enforcement investigations because each person's DNA is different from that of every other individual (except for identical twins). DNA can be extracted from a number of sources, such as hair, bone, teeth, saliva, and blood. As early as the 1980s, states began enacting laws that required collecting DNA samples from offenders convicted of certain sexual and other violent crimes. The samples were then analysed and their profiles entered into state databases. Meanwhile, the FBI laboratory convened a working group of federal, state, and local forensic scientists to establish guidelines for the use of forensic DNA analysis in laboratories. This book provides an overview of how DNA is used to investigate crimes and help protect the innocent. It reviews current statutory law on collecting DNA samples, sharing DNA profiles, and providing access to post-conviction DNA testing.

Modified Nucleic Acids (Hardcover, 1st ed. 2016): Kazuhiko Nakatani, Yitzhak Tor Modified Nucleic Acids (Hardcover, 1st ed. 2016)
Kazuhiko Nakatani, Yitzhak Tor
R3,392 R2,663 Discovery Miles 26 630 Save R729 (21%) Shipped within 7 - 12 working days

This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.

The Initiation of DNA Replication in Eukaryotes (Hardcover, 1st ed. 2016): Daniel L. Kaplan The Initiation of DNA Replication in Eukaryotes (Hardcover, 1st ed. 2016)
Daniel L. Kaplan
R4,512 R4,069 Discovery Miles 40 690 Save R443 (10%) Shipped within 7 - 12 working days

Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of replication initiation is of paramount importance, because once the cell is committed to replicate DNA, it must finish this process. A great deal of progress has been made in understanding how DNA replication is initiated in eukaryotic cells in the past ten years, but this is the first one-source book on these findings. The Initiation of DNA Replication in Eukaryotes will focus on how DNA replication is initiated in eukaryotic cells. While the concept of replication initiation is simple, its elaborate regulation and integration with other cell processes results in a high level of complexity. This book will cover how the position of replication initiation is chosen, how replication initiation is integrated with the phases of the cell cycle, and how it is regulated in the case of damage to DNA. It is the cellular protein machinery that enables replication initiation to be activated and regulated. We now have an in-depth understanding of how cellular proteins work together to start DNA replication, and this new resource will reveal a mechanistic description of DNA replication initiation as well.

Chromatin Signaling and Neurological Disorders (Hardcover): Olivier Binda Chromatin Signaling and Neurological Disorders (Hardcover)
Olivier Binda
R3,005 R2,845 Discovery Miles 28 450 Save R160 (5%) Shipped within 7 - 11 working days

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

Quantum DNA Healing - Consciousness Techniques for Altering Your Genetic Destiny (Paperback): Althea S Hawk Quantum DNA Healing - Consciousness Techniques for Altering Your Genetic Destiny (Paperback)
Althea S Hawk
R308 R196 Discovery Miles 1 960 Save R112 (36%) Shipped within 7 - 12 working days

Sharing the discoveries that enabled her to successfully heal from her cancer, tumors, toxicity, and inflammatory-related conditions, the author explains how genes are not solely responsible for creating disease. She shows how human physiology interacts with the quantum energies of our external and personal environments and how the resulting information triggers the development and persistence of disease and chronic conditions. We each inherit susceptibilities, but it is our unique experience of these environmental factors, as well as our beliefs, thoughts, and emotions, that alter the way our genes are expressed. Detailing how our DNA is both quantum-energetic and biological-chemical, Hawk explains how your environment and your consciousness influence your quantum DNA, which in turn interacts with your biological DNA. By working directly with energetic information that affects how your quantum and biological DNA communicate, you can alter the expression of your genes by re-encoding the gene sequences on your physical DNA, erasing the imprint of illness and enabling your body to remember how to function properly.

RNA Scaffolds - Methods and Protocols (Hardcover, Softcover reprint of the original 1st ed. 2015): Luc Ponchon RNA Scaffolds - Methods and Protocols (Hardcover, Softcover reprint of the original 1st ed. 2015)
Luc Ponchon
R3,455 R2,731 Discovery Miles 27 310 Save R724 (21%) Shipped within 7 - 12 working days

This volume provides techniques on recent developments that use RNA scaffolds as molecular tools. RNA Scaffolds: Methods and Protocols guides readers through methods on various domains as molecular biology, nanotechnologies, and structural biology. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Practical and authoritative, RNA Scaffolds: Methods and Protocols will serve as an invaluable reference for those interested in further study into this fascinating field.

The Maize Genome (Hardcover, 1st ed. 2018): Jeffrey Bennetzen, Sherry Flint-Garcia, Candice Hirsch, Roberto Tuberosa The Maize Genome (Hardcover, 1st ed. 2018)
Jeffrey Bennetzen, Sherry Flint-Garcia, Candice Hirsch, Roberto Tuberosa
R4,428 R3,548 Discovery Miles 35 480 Save R880 (20%) Shipped within 7 - 12 working days

This book discusses advances in our understanding of the structure and function of the maize genome since publication of the original B73 reference genome in 2009, and the progress in translating this knowledge into basic biology and trait improvement. Maize is an extremely important crop, providing a large proportion of the world's human caloric intake and animal feed, and serving as a model species for basic and applied research. The exceptionally high level of genetic diversity within maize presents opportunities and challenges in all aspects of maize genetics, from sequencing and genotyping to linking genotypes to phenotypes. Topics covered in this timely book range from (i) genome sequencing and genotyping techniques, (ii) genome features such as centromeres and epigenetic regulation, (iii) tools and resources available for trait genomics, to (iv) applications of allele mining and genomics-assisted breeding. This book is a valuable resource for researchers and students interested in maize genetics and genomics.

Dictionary of DNA and Genome Technology (Paperback, 3rd Edition): Paul Singleton Dictionary of DNA and Genome Technology (Paperback, 3rd Edition)
Paul Singleton
R971 R708 Discovery Miles 7 080 Save R263 (27%) Shipped within 7 - 13 working days

DNA technology is evolving rapidly, with new methods and a fast-growing vocabulary. This unique dictionary offers current, detailed and accessible information on DNA technology to lecturers, researchers and students throughout the biomedical and related sciences.

The third edition is a major update, with over 3000 references from mainstream journals and data from the very latest research - going well beyond the remit of most science dictionaries. It provides clear explanations of terms, techniques, and tests, including commercial systems, with detailed coverage of many important procedures and methods, and includes essay-style entries on many major topics to assist newcomers to the field. It covers topics relevant to medicine (diagnosis, genetic disorders, gene therapy); veterinary science; biotechnology; biochemistry; pharmaceutical science/drug development; molecular biology; microbiology; epidemiology; genomics; environmental science; plant science/agriculture; taxonomy; and forensic science.

DNA Replication Control in Microbial Cell Factories (Paperback, 2015 ed.): Monika Glinkowska, Lidia Boss, Grzegorz Wegrzyn DNA Replication Control in Microbial Cell Factories (Paperback, 2015 ed.)
Monika Glinkowska, Lidia Boss, Grzegorz Wegrzyn
R1,489 R1,143 Discovery Miles 11 430 Save R346 (23%) Shipped within 7 - 12 working days

This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested.Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
The Tangled Tree - A Radical New History…
David Quammen Hardcover  (1)
R480 R334 Discovery Miles 3 340
Rosalind Franklin
Brenda Maddox Paperback  (3)
R259 R182 Discovery Miles 1 820
Who We Are and How We Got Here - Ancient…
David Reich Paperback  (1)
R282 R209 Discovery Miles 2 090
Tag-based Next Generation Sequencing
Matthias Harbers, Guenter Kahl Hardcover R4,235 R2,976 Discovery Miles 29 760
Francis Crick - Discoverer of the…
Matt Ridley Paperback R231 R161 Discovery Miles 1 610
The Tangled Tree - A Radical New History…
David Quammen Paperback  (1)
R257 R179 Discovery Miles 1 790
Genome Data Analysis
Ju Han Kim Paperback R1,795 R1,420 Discovery Miles 14 200
Blueprint - How DNA Makes Us Who We Are
Robert Plomin Hardcover  (1)
R467 R372 Discovery Miles 3 720
Bioinformatics and Functional Genomics
Jonathan Pevsner Hardcover R2,426 R1,742 Discovery Miles 17 420
Unravelling the Double Helix - The Lost…
Gareth Williams Hardcover  (1)
R487 R392 Discovery Miles 3 920

 

Partners