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Malabsorption in Coeliac Sprue (Paperback, Softcover reprint of the original 1st ed. 1977)
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Malabsorption in Coeliac Sprue (Paperback, Softcover reprint of the original 1st ed. 1977)
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For at least three centuries, Holland has been at the centre of
research on intestinal malabsorption. In the 17th and 18th
centuries, early descriptions of coeliac disease and tropical sprue
were published by physicians trained in Holland, and it was in 1950
that Dicke published his painstaking and vital observations that
coeliac disease in children was caused by the inges tion of wheat
flour. Subsequent careful work with van de Kamer and Weijers showed
that the harmful agent was gluten. Since these discoveries were
made, research in intestinal malabsorption, particularly in the
adult, has continued in several centres in Holland. At Nijmegen,
for example, dr. Cluysenaer, dr. van Tongeren and their as sociates
have been involved in long-term studies of patients with intestinal
disease for the past fifteen years. In this book they describe
their experience of the investigation and treatment of fifty
patients with the adult form of coeliac disease. Their monograph
gives an account of the history, definition and incidence of the
disorder, and then goes on to undertake a critical review of the
pathogenesis of the coeliac lesion. Before embarking on the
different patterns of malabsorption seen in adult coeliac disease,
the authors describe the normal small intestine, its morphology and
function."
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