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Translational Stroke Research - From Target Selection to Clinical Trials (Hardcover, 2012)
Loot Price: R5,793
Discovery Miles 57 930
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Translational Stroke Research - From Target Selection to Clinical Trials (Hardcover, 2012)
Series: Springer Series in Translational Stroke Research
Expected to ship within 10 - 15 working days
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Translational Stroke Research: From Target Selection to Clinical
Trials is part of "Springer Series in Translational Stroke
Research." Forty-three chapters from leading stroke research groups
around the world select future targets and methods for stroke
management such as the vasculature and white matter, protein
aggregation, neuroglobin, microRNAs, oxidation, soluble epoxide
hydrolase, apoptosis, hypoxia-inducible factors, thrombin, toll-
like receptor, angiogenesis, membrane potentials and pumps. The
book discusses methods to regulate brain temperature and the use of
preconditioning in stroke. It also presents new areas of research
emphasizing restoration of function with growth factors and stem
cells. It provides multiple animal models of both ischemic and
hemorrhagic stroke in order to translate basic preclinical findings
to clinical trials with de-risking issues, therapy delivery methods
such as sustained-release and intranasal delivery, and potential
therapies including cell therapies, albumin, transcranial laser,
microbubbles, and ultrasound. Finally, it debates clinical trial
design for analytical methodology, imaging, computation, and
innovations.
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