This book aims to describe the current state of knowledge and
possible future developments in a number of major areas of research
into the nature, causes and treatment of cancer. The contributing
authors have been encouraged to discuss their subjects at the
molecular level. It will become apparent to the reader that
considerable developments in the understanding of the fundamental
nature of cancer, in molecular terms, are constantly being made.
This is particularly the case in the area of oncogene research
where differences between tumour and normal cells can now be
defined in terms of altered expression of DNA sequences. An
understanding of the methods available for detecting cancer, of the
process of carcinogenesis and of the means available for treating
cancer can only be achieved with a precise knowledge of the basic
biochemical and molecular processes involved. Since it is all to
easy for the research scientist to become totally absorbed within
the specialised area of research in which he is involved, the first
chapter is an attempt to encourage a broader field of vision by
introducing the clinician's view of the cancer problem, which
illustrates the broad spectrum of basic problems that need to be
solved by the cancer researcher.
General
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