Progress in Drug Research (Paperback, Softcover reprint of the original 1st ed. 2000)

Hepatitis C virus (HCV) was first identified in 1989 as the etiologic agent of non-A, non-B hepatitis [1] and is currently recognized as the leading cause of chronic liver disease worldwide. In contrast to hepatitis B virus infection, in which only about 5% of adult infections become chronic, more than 80% of HCV-infected patients develop chronic hepatitis. Moreover, 20-50% of those persistently infected with HCV will develop liver cirrhosis and hepatocellu lar carcinoma (HCC) [2]. It is estimated that there are 10,000 deaths in the USA per year due to chronic liver failure or HCC [3]. In addition, HCV dis 25-50% of all liver transplants in US centers, and the ease is responsible for recurrence of HCV infection following liver transplantation is universal [4]. Typically, HCV disease emerges after a 10-20 year period during which symp toms, if they exist at all, are mild and non-specific. Although the prevalence varies greatly among different countries, it has been estimated that up to 170 million people (3% of the world's population), are infected with HCV [5]. A recent study in the USA found that 65% of all HCV-infected persons are 30 to 49 years old [6].

General

Imprint:	Birkhauser Verlag AG
Country of origin:	Switzerland
Series:	Progress in Drug Research, 55
Release date:	October 2012
First published:	2000
Contributors:	Q. May Wang • Beverly A. Heinz • Jay A. Glasel • Gerlie C.de los Reyes • Robert T. Koda • Eric J. Lien • Angelo Vedani • Max Dobler • Paul A. Keifer • Laurane G. Mendelsohn
Dimensions:	254 x 178 x 18mm (L x W x T)
Format:	Paperback
Pages:	336
Edition:	Softcover reprint of the original 1st ed. 2000
ISBN-13:	978-3-03-489544-6
Categories:	Books > Medicine > General issues > General Promotions
LSN:	3-03-489544-5
Barcode:	9783034895446

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