Gaining an understanding of the mechanisms by which cells process
and respond to extracellular cues has become a major goal in many
areas of bi- ogy and has attracted the attentions of almost every
traditional discipline within the biological sciences. At the heart
of these divergent endeavors are common methods that can aid
biochemists, physiologists, and pharmacologists in ta- ling the
specific questions addressed by their research. In Receptor Signal
Transduction Protocols, a diverse array of meth- ologies employed
to interrogate ligand--receptor and receptor-effector int- actions
are described by authors who have devised and successfully applied
them. The authors blend excellent descriptions and applications of
fairly well established methodologies with new technologies at the
cutting-edge of signal transduction research and as such I hope the
present volume will complement and extend a previous excellent
volume in this series edited by David Kendall and Stephen Hill
(Methods Molecular Biology, vol. 41, Signal Transd- tion
Protocols).
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