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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Metabolism
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Iron Metabolism - From Molecular Mechanisms to Clinical Consequences 4e (Hardcover, 4th Edition)
Loot Price: R4,310
Discovery Miles 43 100
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Iron Metabolism - From Molecular Mechanisms to Clinical Consequences 4e (Hardcover, 4th Edition)
Expected to ship within 12 - 19 working days
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Iron is indispensable for the growth, development and well-being of
almost all living organisms. Biological systems from bacteria,
fungi and plants to humans have evolved systems for the uptake,
utilisation, storage and homeostasis of iron. Its importance for
microbial growth makes its uptake systems a natural target for
pathogenic microorganisms and parasites. Uniquely, humans suffer
from both iron deficiency and iron overload, while the capacity of
iron to generate highly reactive free radicals, causing oxidative
stress, is associated with a wide range of human pathologies,
including many neurodegenerative diseases. Whereas some essential
metal ions like copper and zinc are closely linked with iron
metabolism, toxic metals like aluminium and cadmium can interfere
with iron metabolism. Finally, iron metabolism and homeostasis are
key targets for the development of new drugs for human health. The
4th edition of Iron Metabolism is written in a lively style by one
of the leaders in the field, presented in colour and covers the
latest discoveries in this exciting area. It will be essential
reading for researchers and students in biochemistry, molecular
biology, microbiology, cell biology, nutrition and medical
sciences. Other interested groups include biological inorganic
chemists with an interest in iron metabolism, health professionals
with an interest in diseases of iron metabolism, or of diseases in
which iron uptake systems are involved (eg. microbial and fungal
infections, cancer, neurodegenerative disorders), and researchers
in the pharmaceutical industry interested in developing novel drugs
targeting iron metabolism/homeostasis.
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