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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Stem Cells for Myocardial Regeneration - Methods and Protocols (Hardcover, 2010)
Loot Price: R2,940
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Stem Cells for Myocardial Regeneration - Methods and Protocols (Hardcover, 2010)
Series: Methods in Molecular Biology, 660
Expected to ship within 10 - 15 working days
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The feld of regenerative medicine is in its infancy state.
Enthusiasm for the potential of organ regeneration lies with the
potential pluripotency of stem cells to differentiate into various
tissue types. This volume of Methods in Molecular Biology will
focus on the use of stem cells for myocardial repair and
regeneration. The emphasis of this issue will be to provide basic
scientists, translational investigators, and cardiologists a means
to evaluate the effcacy and safety of stem cells in a standardized
fashion for myocardial regeneration. Many different cell types have
been considered for myocardial repair. Adult card- myocytes are
unable to survive even when transplanted into normal myocardium.
The use of fetal or neonatal cardiomyocytes is not a feasible
source of cells due to ethical concerns and donor availability.
Therefore, the use of pluripotent stem cells has become the focus
of a cell source for myocardial repair and regeneration. A variety
of stem cell types have been suggested to participate in myocardial
repair. This has led the investigators to search for the "optimal
cell type for myocardial repair". Reliable isolation of the cell
source with the ability to expand the cell population is a
prerequisite. In the frst section of this book, methods for
isolation of commonly used stem cells being investigated for
myocardial regeneration are presented. Once a stem cell source has
been selected, the stem cell needs to be tested in an app- priate
animal model before being translated into clinical practice.
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